Biosilicification Templated by Amphiphilic Block Copolypeptide Assemblies

doi:10.1002/mabi.201000297

CORC > 化学研究所 > 中国科学院化学研究所

	Biosilicification Templated by Amphiphilic Block Copolypeptide Assemblies
	Xia, Lin; Liu, Yu; Li, Zhibo
刊名	MACROMOLECULAR BIOSCIENCE
	2010-12-08
卷号	10 期号:12 页码:1566-1575
关键词	Amphiphiles Biomimetics Biomineralization Diblock Copolymers Morphology Self-assembly
ISSN号	1616-5187
DOI	10.1002/mabi.201000297
英文摘要	An amphiphilic poly(L-lysine.HBr)-block-poly(L-leucine) (KL) diblock copolypeptide and its supramolecular assembly are used as a template to direct silica formation, which proceeds by a cooperative process involving biomimetic mineralization and copolypetide reassembly under ambient conditions. Various silica structures can be obtained by using different counterions, changing the chain length of the KL diblocks, and applying a sol-gel mineralization method. We find that the chain length of the KL diblock is an important factor in terms of controlling biosilica morphologies. We also find that the nature of the counterions strongly affects the resulting silica structures. For the same KL diblock, variation of anions from phosphate to sulfate and to carbonate can produce hexagonal silica platelets, silica rods, and fused silica platelets, respectively. In contrast, application of a sol-gel method can replicate the copolypeptide fibril network morphology in water, while employment of ultrasonication to the sol-gel medium transforms the silica fibrils to rigid silica rods. The resulting silica morphology has been systematically characterized using SEM and TEM, and the polypeptide conformation is explored using FT-IR and CD spectroscopy.
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000285313000019
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/71001]
专题	中国科学院化学研究所
通讯作者	Li, Zhibo
作者单位	Chinese Acad Sci, BNLMS, Inst Chem, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Xia, Lin,Liu, Yu,Li, Zhibo. Biosilicification Templated by Amphiphilic Block Copolypeptide Assemblies[J]. MACROMOLECULAR BIOSCIENCE,2010,10(12):1566-1575.
APA	Xia, Lin,Liu, Yu,&Li, Zhibo.(2010).Biosilicification Templated by Amphiphilic Block Copolypeptide Assemblies.MACROMOLECULAR BIOSCIENCE,10(12),1566-1575.
MLA	Xia, Lin,et al."Biosilicification Templated by Amphiphilic Block Copolypeptide Assemblies".MACROMOLECULAR BIOSCIENCE 10.12(2010):1566-1575.