pH-Sensitive Micelles Based on Double-Hydrophilic Poly(methylacrylic acid)-Poly(ethylene glycol)-Poly(methylacrylic acid) Triblock Copolymer

doi:10.1007/s11671-009-9249-2

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	pH-Sensitive Micelles Based on Double-Hydrophilic Poly(methylacrylic acid)-Poly(ethylene glycol)-Poly(methylacrylic acid) Triblock Copolymer
	Tao, Youhua 1,2; Liu, Ren 2,3; Liu, Xiaoya 2,3; Chen, Mingqing 2,3; Yang, Cheng 2,3; Ni, Zhongbin 2,3
刊名	NANOSCALE RESEARCH LETTERS
	2009-04-01
卷号	4 期号:4 页码:341-343
关键词	Self-assembly Micelles Double-hydrophilic Triblock Copolymers
ISSN号	1931-7573
DOI	10.1007/s11671-009-9249-2
英文摘要	pH-sensitive micelles with hydrophilic core and hydrophilic corona were fabricated by self-assembling of triblock copolymer of poly(methylacrylic acid)-poly(ethylene glycol)-poly(methylacrylic acid) at lower solution pH. Transmission electron microscopy and laser light scattering studies showed micelles were in nano-scale with narrow size distribution. Solution pH value and the micelles concentration strongly influenced the hydrodynamic radius of the spherical micelles (48-310 nm). A possible mechanism for the formation of micelles was proposed. The obtained polymeric micelle should be useful for biomedical materials such as carrier of hydrophilic drug.
语种	英语
出版者	SPRINGER
WOS记录号	WOS:000263116500009
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/67941]
专题	中国科学院化学研究所
通讯作者	Liu, Xiaoya
作者单位	1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Jiangnan Univ, Sch Chem & Mat Engn, Wuxi 214122, Peoples R China 3.Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi 214122, Peoples R China
推荐引用方式 GB/T 7714	Tao, Youhua,Liu, Ren,Liu, Xiaoya,et al. pH-Sensitive Micelles Based on Double-Hydrophilic Poly(methylacrylic acid)-Poly(ethylene glycol)-Poly(methylacrylic acid) Triblock Copolymer[J]. NANOSCALE RESEARCH LETTERS,2009,4(4):341-343.
APA	Tao, Youhua,Liu, Ren,Liu, Xiaoya,Chen, Mingqing,Yang, Cheng,&Ni, Zhongbin.(2009).pH-Sensitive Micelles Based on Double-Hydrophilic Poly(methylacrylic acid)-Poly(ethylene glycol)-Poly(methylacrylic acid) Triblock Copolymer.NANOSCALE RESEARCH LETTERS,4(4),341-343.
MLA	Tao, Youhua,et al."pH-Sensitive Micelles Based on Double-Hydrophilic Poly(methylacrylic acid)-Poly(ethylene glycol)-Poly(methylacrylic acid) Triblock Copolymer".NANOSCALE RESEARCH LETTERS 4.4(2009):341-343.