Thermomorphic system with non-fluorous phase-tagged Ru(BINAP) catalyst: Facile liquid/solid catalyst separation and application in asymmetric hydrogenation

doi:10.1021/jo052092m

CORC > 化学研究所 > 中国科学院化学研究所

	Thermomorphic system with non-fluorous phase-tagged Ru(BINAP) catalyst: Facile liquid/solid catalyst separation and application in asymmetric hydrogenation
	Huang, YY ; He, YM ; Zhou, HF ; Wu, L ; Li, BL ; Fan, QH
刊名	JOURNAL OF ORGANIC CHEMISTRY
	2006-03-31
卷号	71 期号:7 页码:2874-2877
ISSN号	0022-3263
DOI	10.1021/jo052092m
英文摘要	The thermomorphic BINAP derivative 1 tagged with long alkyl chains was prepared from (S)-5,5'-diamino BINAP and applied to Ru-catalyzed asymmetric hydrogenation of beta-ketoesters under homogeneous conditions in 3:1 (v/v) ethanol/1,4-dioxane at 60 degrees C with high enantioselectivity (up to 98% ee). Results indicated that the Ru(1) catalyst was easily recovered by simple cooling and precipitation and could be used for at least four cycles without any loss of enantioselectivity.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000236652200042
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/59709]
专题	中国科学院化学研究所
通讯作者	Fan, QH
作者单位	1.Chinese Acad Sci, Inst Chem, Biol Chem Lab, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Huang, YY,He, YM,Zhou, HF,et al. Thermomorphic system with non-fluorous phase-tagged Ru(BINAP) catalyst: Facile liquid/solid catalyst separation and application in asymmetric hydrogenation[J]. JOURNAL OF ORGANIC CHEMISTRY,2006,71(7):2874-2877.
APA	Huang, YY,He, YM,Zhou, HF,Wu, L,Li, BL,&Fan, QH.(2006).Thermomorphic system with non-fluorous phase-tagged Ru(BINAP) catalyst: Facile liquid/solid catalyst separation and application in asymmetric hydrogenation.JOURNAL OF ORGANIC CHEMISTRY,71(7),2874-2877.
MLA	Huang, YY,et al."Thermomorphic system with non-fluorous phase-tagged Ru(BINAP) catalyst: Facile liquid/solid catalyst separation and application in asymmetric hydrogenation".JOURNAL OF ORGANIC CHEMISTRY 71.7(2006):2874-2877.