Synthesis and characterization of a six-coordinate monomeric Mn(III) complex with SOD-like activity

doi:10.1080/00958970500249814

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	Synthesis and characterization of a six-coordinate monomeric Mn(III) complex with SOD-like activity
	Shi, W ; Liu, Y ; Liu, B ; Song, YG ; Xu, YK ; Wang, HM ; Sha, YL ; Xu, GZ ; Styring, S ; Huang, P
刊名	JOURNAL OF COORDINATION CHEMISTRY
	2006-01-20
卷号	59 期号:2 页码:119-130
关键词	Manganese(Iii) 2-o-hydroxyphenylbenzimidazole Pyridine X-ray Structure Superoxide Dismutase Superoxide Ion Reactivity Spin Trap Pyrogallol Autoxidation 2 2-dimethyl-3 4-dihydro-2h-pyrrole-1-oxide
ISSN号	0095-8972
DOI	10.1080/00958970500249814
英文摘要	The complex [Mn-III(HL)(L)(py)(CH3OH)](CH3OH)-C-. (H2L=2-ortho-hydroxyphenylbenzimidazole, py pyridine), 1, has been characterized spectroscopically and by X-ray crystallography. The complex is triclinic, space group P-1(-) with a = 10.396(2), b = 10.7340(10), c = 15.193(2) angstrom, alpha = 73.193(4)degrees, beta = 76.283(8)degrees, gamma = 61.400(40)degrees, V = 1415.1(4)angstrom(3), Z = 2, D-c = 1.445 Mg m(-3), M-r = 615.56, mu = 0.515 mm(-1), F(000) = 640, R = 0.0631, wR = 0.1525. Manganese is six-coordinate in an N3O3 ligand sphere created by two bidentate H2L ligands and solvent molecules with a slightly distorted, axially elongated octahedral geometry. Electronic absorption spectra show pi-pi* and Ligand Metal Charge Transfer (LMCT) transitions in the UV region and d-d transitions in the visible region. Solvent molecules coordinated to the Mn(III) ion in the crystal are thought to retain their coordination in solution. It is shown that 1 has reaction activity with the superoxide ion, as indicated by inhibition of pyrogallol autoxidation and by spin trapping electron paramagnetic resonance (EPR) spectroscopy. The N3O3 ligand set in 1 is similar to that in native MnSOD (superoxide dismutatase) in the substrate-bound state. The correlation between the ligand set in 1 and its reaction with the superoxide ion is discussed.
语种	英语
出版者	TAYLOR & FRANCIS LTD
WOS记录号	WOS:000235500600001
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/59391]
专题	中国科学院化学研究所
通讯作者	Liu, Y
作者单位	1.Chinese Acad Sci, State Key Lab Struct Chem Unstable & Stable Speci, Ctr Mol Sci, Inst Chem, Beijing 100080, Peoples R China 2.Peking Univ, Sch Basic Med Sci, Dept Biophys, Beijing 10083, Peoples R China 3.Uppsala Univ, Dept Mol Biomimet, S-75236 Uppsala, Sweden 4.Lund Univ, Ctr Chem & Chem Engn, Dept Biochem, S-22100 Lund, Sweden
推荐引用方式 GB/T 7714	Shi, W,Liu, Y,Liu, B,et al. Synthesis and characterization of a six-coordinate monomeric Mn(III) complex with SOD-like activity[J]. JOURNAL OF COORDINATION CHEMISTRY,2006,59(2):119-130.
APA	Shi, W.,Liu, Y.,Liu, B.,Song, YG.,Xu, YK.,...&Huang, P.(2006).Synthesis and characterization of a six-coordinate monomeric Mn(III) complex with SOD-like activity.JOURNAL OF COORDINATION CHEMISTRY,59(2),119-130.
MLA	Shi, W,et al."Synthesis and characterization of a six-coordinate monomeric Mn(III) complex with SOD-like activity".JOURNAL OF COORDINATION CHEMISTRY 59.2(2006):119-130.