Synthesis and characterization of electro-active and biodegradable block copolymer of aniline pentamer with polylactide

CORC > 化学研究所 > 中国科学院化学研究所

	Synthesis and characterization of electro-active and biodegradable block copolymer of aniline pentamer with polylactide
	Huang, LH ; Hu, J ; Zhuang, XL ; Ma, J ; Chen, XS ; Jing, XB ; Guo, Y ; Li, MY ; Lelkes, PI ; Wei, Y
刊名	CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
	2005-09-10
卷号	26 期号:9 页码:1771-1773
关键词	Polylactide Aniline Pentamer Electrical Activity Biodegradablility
ISSN号	0251-0790
英文摘要	Every slight movement of human body, such as beat of heart, contract of muscles, thinking of brain, is associated with bioelectricity. In search for a neural conducting tissue engineering material which can ideally conduct bioelectrical signals in vivo, the block copolymer of polylactide(PLA) and aniline pentamer - a material which is electro-active, remarkably biocompatible and biodegradable, was designed and synthesized. The aniline pentamer is similar with polyaniline in electrical chemical properties, but more soluble than the latter. The copolymer is prepared by condensation polymerization between carboxyl-capped aniline pentamer and dihydroxyl-capped PLA, with N,N '-dicyclohexylcarbodiimide (DCC) as a condensing agent. The co-polymerization of aniline pentarner and PIA can not only reduce the toxicity of aniline pentamer, but also make the material easily to degrade and excrete from the body. These properties of the copolymer provide a favorable prospect in biomedical application in vivo. The synthesized material is investigated by FTIR, H-1 NMR, UV, and cyclic voltammetric measurements.
语种	英语
出版者	HIGHER EDUCATION PRESS
WOS记录号	WOS:000232081400047
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/57461]
专题	中国科学院化学研究所
通讯作者	Chen, XS
作者单位	1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Drexel Univ, Dept Chem, Philadelphia, PA 19104 USA
推荐引用方式 GB/T 7714	Huang, LH,Hu, J,Zhuang, XL,et al. Synthesis and characterization of electro-active and biodegradable block copolymer of aniline pentamer with polylactide[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2005,26(9):1771-1773.
APA	Huang, LH.,Hu, J.,Zhuang, XL.,Ma, J.,Chen, XS.,...&Wei, Y.(2005).Synthesis and characterization of electro-active and biodegradable block copolymer of aniline pentamer with polylactide.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,26(9),1771-1773.
MLA	Huang, LH,et al."Synthesis and characterization of electro-active and biodegradable block copolymer of aniline pentamer with polylactide".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 26.9(2005):1771-1773.