Exploring the optimal ratio of D-glucose/L-aspartic acid for targeting carbon dots toward brain tumor cells

doi:10.1016/j.msec.2017.12.011

CORC > 化学研究所 > 中国科学院化学研究所

	Exploring the optimal ratio of D-glucose/L-aspartic acid for targeting carbon dots toward brain tumor cells
	Qiao, Lihong 1; Sun, Tingting 2,3; Zheng, Xiaohua 2,3; Zheng, Min 1; Xie, Zhigang 2
刊名	MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
	2018-04-01
卷号	85 页码:1-6
关键词	Optimal Ratio D-glucose L-aspartic Acid Carbon Dots Targeting Brain Cancer
ISSN号	0928-4931
DOI	10.1016/j.msec.2017.12.011
英文摘要	Targeting imaging to the desired site of action can increase the accuracy and effectiveness of diagnostic and treatment. In this work, a series of fluorescent carbon dots (CDs) were prepared by varying molar ratios of D-glucose (Glu) to L-aspartic acid (Asp). Their photophysical properties, morphologies and structures were investigated in detail. More important, the targeting ability was screened by confocal laser scanning microscopy and flow cytometry. The results indicate that CDs prepared from the optimal molar ratio of Glu/Asp (7:3) exhibit the highest targeting ability on C6 glioma cells, This work highlights the interplay of molecular design and corresponding functions, and open new possibility of developing state-of-art nanoparticles for biomedical applications.
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000428496400001
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/46131]
专题	中国科学院化学研究所
通讯作者	Zheng, Min; Xie, Zhigang
作者单位	1.Changchun Univ Technol, Sch Chem & Life Sci, Adv Inst Mat Sci, 2055 Yanan St, Changchun 130012, Jilin, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, 5625 Renmin St, Changchun 130022, Jilin, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Qiao, Lihong,Sun, Tingting,Zheng, Xiaohua,et al. Exploring the optimal ratio of D-glucose/L-aspartic acid for targeting carbon dots toward brain tumor cells[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2018,85:1-6.
APA	Qiao, Lihong,Sun, Tingting,Zheng, Xiaohua,Zheng, Min,&Xie, Zhigang.(2018).Exploring the optimal ratio of D-glucose/L-aspartic acid for targeting carbon dots toward brain tumor cells.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,85,1-6.
MLA	Qiao, Lihong,et al."Exploring the optimal ratio of D-glucose/L-aspartic acid for targeting carbon dots toward brain tumor cells".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 85(2018):1-6.