Controlled movement of kinesin-driven microtubule along a directional track

doi:10.1016/j.colsurfa.2018.04.049

CORC > 化学研究所 > 中国科学院化学研究所

	Controlled movement of kinesin-driven microtubule along a directional track
	Xia, Jiarui 1,2; Sun, Bingbing 1,3; Yang, Yang 2; Li, Jieling 1; Jia, Yi 1; Dong, Weiguang 1; Li, Junbai 1,3
刊名	COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
	2018-08-05
卷号	550 页码:186-192
关键词	Surface Modification Kinesin Microtubule Controlled Movement Nanodevice
ISSN号	0927-7757
DOI	10.1016/j.colsurfa.2018.04.049
英文摘要	We designed a system for the controlled directional movements of kinesin-driven microtubule by restricting the motor coating areas in a two-dimensional (2D) substrate. The t-butoxycarbonyl (Boc) was firstly introduced in an amine groups modified glass surface to construct 2D track. The polarity of the above mentioned glass can be efficiently reversed after Boc protection, resulting in the surface transferring from hydrophilicity to hydrophobicity. Through a selective treatment of Boc de-protection, the substrate surface can be distributed into hydrophilic and hydrophobic partitions. The hydrophilic areas can be observed by labeling nanoparticles or fluorescent dye, thus the different shapes were formed at the substrate. The hydrophilic parts in the substrates will allow kinesin to be selectively immobilized on this surface and result in the controlled directional movement of microtubule. With this design, the selective decoration of 2D tracks may have a potential application in field of biomolecular motors based nanodevice.
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000432552600022
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/42803]
专题	中国科学院化学研究所
通讯作者	Jia, Yi; Li, Junbai
作者单位	1.Chinese Acad Sci, Inst Chem, BNLMS, CAS Key Lab Colloid Interface & Chem Thermodynam, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Xia, Jiarui,Sun, Bingbing,Yang, Yang,et al. Controlled movement of kinesin-driven microtubule along a directional track[J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,2018,550:186-192.
APA	Xia, Jiarui.,Sun, Bingbing.,Yang, Yang.,Li, Jieling.,Jia, Yi.,...&Li, Junbai.(2018).Controlled movement of kinesin-driven microtubule along a directional track.COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,550,186-192.
MLA	Xia, Jiarui,et al."Controlled movement of kinesin-driven microtubule along a directional track".COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 550(2018):186-192.