Catalytic Asymmetric Oxidative Enamine Transformations

doi:10.1021/acscatal.8b01263

CORC > 化学研究所 > 中国科学院化学研究所

	Catalytic Asymmetric Oxidative Enamine Transformations
	Zhu, Lihui 1,2; Wang, Dehong 1,2; Jia, Zongbin 1,2; Lin, Qifeng 1,2; Huang, Mouxin 3; Luo, Sanzhong 1,2,3,4
刊名	ACS CATALYSIS
	2018-06-01
卷号	8 期号:6 页码:5466-5484
关键词	Organocatalysis Aminocatalysis Enamine Transformation Oxidative Enamine Catalysis Nucleophile
ISSN号	2155-5435
DOI	10.1021/acscatal.8b01263
英文摘要	Enamine catalysis is a prevalent strategy for the fiinctionalization of aldehydes/ketones with electrophiles. Recently, the advent and development of oxidative enamine catalysis have allowed for the coupling of enamines with readily available nucleophiles under oxidative conditions, significantly expanding the domain of typical enamine catalysis. In this perspective, we summarize the recent advances in asymmetric oxidative enamine catalysis. On the basis of the oxidative strategy, these could be classified as (1) oxidation of nucleophile, (2) oxidation of enamine via single-electron transfer (SOMO catalysis), and (3) oxidation of enamine to alpha,beta-unsaturated iminium ion, i.e. oxidative iminium catalysis. These strategies have enabled efficient oxidative functionalizations of aldehydes/ketones with various O-, N-, and C-centered nucleophiles in a highly stereocontrolled manner.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000434369600077
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/42739]
专题	中国科学院化学研究所
通讯作者	Luo, Sanzhong
作者单位	1.Chinese Acad Sci, Inst Chem, Key Lab Mol Recognit & Funct, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100490, Peoples R China 3.Tsinghua Univ, CBMS, Dept Chem, Beijing 100084, Peoples R China 4.Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China
推荐引用方式 GB/T 7714	Zhu, Lihui,Wang, Dehong,Jia, Zongbin,et al. Catalytic Asymmetric Oxidative Enamine Transformations[J]. ACS CATALYSIS,2018,8(6):5466-5484.
APA	Zhu, Lihui,Wang, Dehong,Jia, Zongbin,Lin, Qifeng,Huang, Mouxin,&Luo, Sanzhong.(2018).Catalytic Asymmetric Oxidative Enamine Transformations.ACS CATALYSIS,8(6),5466-5484.
MLA	Zhu, Lihui,et al."Catalytic Asymmetric Oxidative Enamine Transformations".ACS CATALYSIS 8.6(2018):5466-5484.