N-Heterocyclic Carbene-Catalyzed Annulation of alpha-Chloroaldehydes with gamma-/delta-Amino-alpha,beta-Unsaturated Ketones: Enantioselective Synthesis of Pyrrolidones and Piperidones

doi:10.1002/chem.201801539

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	N-Heterocyclic Carbene-Catalyzed Annulation of alpha-Chloroaldehydes with gamma-/delta-Amino-alpha,beta-Unsaturated Ketones: Enantioselective Synthesis of Pyrrolidones and Piperidones
	Zhang, Zhao-Fei 1,2; Zhang, Chun-Lin 1,2; Song, Zhi-Yong 1,2; Gao, Zhong-Hua 1,2; Ye, Song 1,2
刊名	CHEMISTRY-A EUROPEAN JOURNAL
	2018-06-12
卷号	24 期号:33 页码:8302-8305
关键词	Annulation Carbene Catalysis Enantioselectivity Piperidones Pyrrolidones
ISSN号	0947-6539
DOI	10.1002/chem.201801539
英文摘要	The N-heterocyclic carbene-catalyzed [2+3] and [2+4] annulations of alpha-chloroaldehydes with gamma-/delta-amino-alpha,beta-unsaturated ketones were developed, giving the corresponding pyrrolidones and piperidones in good yields with exclusive trans-selectivities and excellent enantioselectivities.
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000435269000010
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/42501]
专题	中国科学院化学研究所
通讯作者	Ye, Song
作者单位	1.Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Zhao-Fei,Zhang, Chun-Lin,Song, Zhi-Yong,et al. N-Heterocyclic Carbene-Catalyzed Annulation of alpha-Chloroaldehydes with gamma-/delta-Amino-alpha,beta-Unsaturated Ketones: Enantioselective Synthesis of Pyrrolidones and Piperidones[J]. CHEMISTRY-A EUROPEAN JOURNAL,2018,24(33):8302-8305.
APA	Zhang, Zhao-Fei,Zhang, Chun-Lin,Song, Zhi-Yong,Gao, Zhong-Hua,&Ye, Song.(2018).N-Heterocyclic Carbene-Catalyzed Annulation of alpha-Chloroaldehydes with gamma-/delta-Amino-alpha,beta-Unsaturated Ketones: Enantioselective Synthesis of Pyrrolidones and Piperidones.CHEMISTRY-A EUROPEAN JOURNAL,24(33),8302-8305.
MLA	Zhang, Zhao-Fei,et al."N-Heterocyclic Carbene-Catalyzed Annulation of alpha-Chloroaldehydes with gamma-/delta-Amino-alpha,beta-Unsaturated Ketones: Enantioselective Synthesis of Pyrrolidones and Piperidones".CHEMISTRY-A EUROPEAN JOURNAL 24.33(2018):8302-8305.