Antioxidant xanthones from Swertia mussotii, a high altitude plant

	Antioxidant xanthones from Swertia mussotii, a high altitude plant
	Luo, Cui-Ting ; Mao, Shuang-Shuang ; Liu, Fang-Lan ; Yang, Mao-xun ; Chen, Heru ; Kurihara, Hiroshi ; Li, Yulin ; Chen, HR (reprint author), Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Huangpu Ave West 601, Guangzhou 510632, Guangdong, Peoples R China.
刊名	FITOTERAPIA ; Luo, CT; Mao, SS; Liu, FL; Yang, MX; Chen, HR; Kurihara, H; Li, YL.Antioxidant xanthones from Swertia mussotii, a high altitude plant,FITOTERAPIA,2013,91():140-147
	2013-12-01
英文摘要	Four new xanthones, 3,5,6,8-tetrahydroxyxanthone-1-C-beta-D-glucoside (1), 7-hydroxy-3,4,8-trimethoxyxanthone-1-O-(beta-D-glucoside) (2), 6-hydroxy-3,5-dimethoxyxanthone-1-O-(beta-D-glucoside) (3), 3,4,7,8-tetramethoxyxanthone-1-O-(beta-D-glucoside) (4), together with twenty-one known xanthones (5-25) were isolated from the ethanol aqueous extract of Swertia mussotii. Their structures were elucidated via spectroscopic analyses. Oxygen radical absorbance capacity of all the isolated xanthones was systematically evaluated by ORAC(FL) assay. Results disclose that all the tested xanthones display moderate to excellent antioxidant activity, where I is the most active compound and 13 is the least one. A preliminary structure-activity relationship is also discussed. (C) 2013 Elsevier B.V. All rights reserved.; Four new xanthones, 3,5,6,8-tetrahydroxyxanthone-1-C-beta-D-glucoside (1), 7-hydroxy-3,4,8-trimethoxyxanthone-1-O-(beta-D-glucoside) (2), 6-hydroxy-3,5-dimethoxyxanthone-1-O-(beta-D-glucoside) (3), 3,4,7,8-tetramethoxyxanthone-1-O-(beta-D-glucoside) (4), together with twenty-one known xanthones (5-25) were isolated from the ethanol aqueous extract of Swertia mussotii. Their structures were elucidated via spectroscopic analyses. Oxygen radical absorbance capacity of all the isolated xanthones was systematically evaluated by ORAC(FL) assay. Results disclose that all the tested xanthones display moderate to excellent antioxidant activity, where I is the most active compound and 13 is the least one. A preliminary structure-activity relationship is also discussed. (C) 2013 Elsevier B.V. All rights reserved.
内容类型	期刊论文
源URL	[http://210.75.249.4/handle/363003/3894]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Luo, Cui-Ting,Mao, Shuang-Shuang,Liu, Fang-Lan,et al. Antioxidant xanthones from Swertia mussotii, a high altitude plant[J]. FITOTERAPIA, Luo, CT; Mao, SS; Liu, FL; Yang, MX; Chen, HR; Kurihara, H; Li, YL.Antioxidant xanthones from Swertia mussotii, a high altitude plant,FITOTERAPIA,2013,91():140-147,2013.
APA	Luo, Cui-Ting.,Mao, Shuang-Shuang.,Liu, Fang-Lan.,Yang, Mao-xun.,Chen, Heru.,...&Chen, HR .(2013).Antioxidant xanthones from Swertia mussotii, a high altitude plant.FITOTERAPIA.
MLA	Luo, Cui-Ting,et al."Antioxidant xanthones from Swertia mussotii, a high altitude plant".FITOTERAPIA (2013).