Simultaneous Determination of Food-Related Biogenic Amines and Precursor Amino Acids Using in Situ Derivatization Ultrasound-Assisted Dispersive Liquid-Liquid Microextraction by Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry

	Simultaneous Determination of Food-Related Biogenic Amines and Precursor Amino Acids Using in Situ Derivatization Ultrasound-Assisted Dispersive Liquid-Liquid Microextraction by Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry
	He, Yongrui ; Zhao, Xian-En ; Wang, Renjun ; Wei, Na ; Sun, Jing ; Dang, Jun ; Chen, Guang ; Liu, Zhiqiang ; Zhu, Shuyun ; You, Jinmao
刊名	JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
	2016-11-02
英文摘要	A simple, rapid, sensitive, selective, and environmentally friendly method; based on in situ derivatization ultrasound-assisted dispersive liquid-liquid microextraction (in situ DUADLLME) coupled with ultra-high-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) using multiple reaction monitoring (MRM) mode has been developed for the simultaneous determination of food-related biogenic amines and amino acids. A new mass-spectrometry sensitive derivatization reagent 4'-carbonyl chloride rosamine (CCR) was designed, synthesized, and first reported. Parameters and conditions of in situ DUADLLME and UHPLC-MS/MS were, optimized in detail. Under the optimized conditions, the in situ DUADLLME was completed speedily (within 1 min) with high derivatization efficiencies (>= 98.5%). With the cleanup and concentration of microextraction step, good analytical performance was obtained for the analytes. The results showed that this method was accurate and practical for quantification of biogenic amines and amino acids in common food samples (red wine, beer, wine, cheese, sausage, and fish).
内容类型	期刊论文
源URL	[http://210.75.249.4/handle/363003/6411]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	He, Yongrui,Zhao, Xian-En,Wang, Renjun,et al. Simultaneous Determination of Food-Related Biogenic Amines and Precursor Amino Acids Using in Situ Derivatization Ultrasound-Assisted Dispersive Liquid-Liquid Microextraction by Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2016.
APA	He, Yongrui.,Zhao, Xian-En.,Wang, Renjun.,Wei, Na.,Sun, Jing.,...&You, Jinmao.(2016).Simultaneous Determination of Food-Related Biogenic Amines and Precursor Amino Acids Using in Situ Derivatization Ultrasound-Assisted Dispersive Liquid-Liquid Microextraction by Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.
MLA	He, Yongrui,et al."Simultaneous Determination of Food-Related Biogenic Amines and Precursor Amino Acids Using in Situ Derivatization Ultrasound-Assisted Dispersive Liquid-Liquid Microextraction by Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2016).