Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection Technique

doi:10.3390/s19051148

	Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection Technique
	Yu, Miao 1,2; Yan, Shihan3,4 ; Sun, Yong-qiang 1; Sheng, Wang 2; Tang, Fu 2; Peng, Xiao-yu2 ; Hu, Yuan 1
刊名	SENSORS
	2019-03-01
卷号	19 期号:5 页码:11
关键词	THz-TDS THz-ABCD system fingerprint spectrum nucleobase
ISSN号	1424-8220
DOI	10.3390/s19051148
通讯作者	Yan, Shihan(yanshihan@cigit.ac.cn) ; Peng, Xiao-yu(xypeng@cigit.ac.cn) ; Hu, Yuan(huy@cust.edu.cn)
英文摘要	Terahertz time-domain spectroscopy (THz-TDS) is an effective coherent detection technique for deeply understanding the structures and functions of biomolecules. However, generally not full information in the whole THz range can be obtained due to the limited detection bandwidth (usually less than 5 THz) of the traditional THz-TDS systems. In this paper, effective THz absorption spectra in 0.5-10 THz range of five typical nucleobases of DNA/RNA are characterized with a super broadband THz detection technique, called the air-biased- coherent-detection (THz-ABCD) technique. Few unexpected characteristic absorption peaks appeared in the low-frequency region and meanwhile a series of anticipated characteristic absorption peaks are found in the high-frequency region. The fingerprint spectra of these nucleobases are helpful for further analysis on the vibration and twisting behavior of hydrogen bonds, van der Waals and electrostatic forces etc. between and within DNA/RNA biomolecules.
资助项目	National Key Basic Research Program of China (973 Program)[2015CB755401] ; Natural Science Foundation of China (NSFC)[11504372] ; Key Project of the Special Fund for Research in Basic Science and Frontier Technology in Chongqing[cstc2015jcyjBX0030] ; Technology Innovation and Application Demonstration Research Project of Chongqing[cstc2018jscx-msybX0084] ; National Key R&D Program of China[2016YFC0101301]
WOS研究方向	Chemistry ; Electrochemistry ; Instruments & Instrumentation
语种	英语
出版者	MDPI
WOS记录号	WOS:000462540400167
内容类型	期刊论文
源URL	[http://119.78.100.138/handle/2HOD01W0/7640]
专题	中国科学院重庆绿色智能技术研究院
通讯作者	Yan, Shihan; Peng, Xiao-yu; Hu, Yuan
作者单位	1.Changchun Univ Sci & Technol, Minist Educ, Key Lab Optoelect Measurement & Opt Informat Tran, Changchun 130022, Jilin, Peoples R China 2.Chinese Acad Sci, Terahertz Technol Res Ctr, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China 3.Chinese Acad Sci, Ctr Appl Phys, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China 4.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing Engn Res Ctr High Resolut & Three Dimen, Chongqing 400714, Peoples R China
推荐引用方式 GB/T 7714	Yu, Miao,Yan, Shihan,Sun, Yong-qiang,et al. Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection Technique[J]. SENSORS,2019,19(5):11.
APA	Yu, Miao.,Yan, Shihan.,Sun, Yong-qiang.,Sheng, Wang.,Tang, Fu.,...&Hu, Yuan.(2019).Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection Technique.SENSORS,19(5),11.
MLA	Yu, Miao,et al."Characterization of Nucleobases in Broadband Terahertz Spectra from 0.5 to 10 THz with the Air-Biased-Coherent-Detection Technique".SENSORS 19.5(2019):11.