Peptide-modulated self-assembly as a versatile strategy for tumor supramolecular nanotheranostics | |
Li, Shukun1,3; Zou, Qianli1; Xing, Ruirui1; Govindaraju, Thimmaiah4; Fakhrullin, Rawil5; Yan, Xuehai1,2,3 | |
刊名 | THERANOSTICS |
2019 | |
卷号 | 9期号:11页码:3249-3261 |
关键词 | peptides self-assembly intermolecular interactions nanotheranostics cancer |
ISSN号 | 1838-7640 |
DOI | 10.7150/thno.31814 |
英文摘要 | Advances in supramolecular self-assembly have promoted the development of theranostics, the combination of both therapeutic and diagnostic functions in a single nanoplatform, which is closely associated with antitumor applications and has shown promising potential in personalized medicine. Peptide-modulated self-assembly serves as a versatile strategy for tumor supramolecular nanotheranostics possessing controllability, programmability, functionality and biosafety, thus promoting the translation of nanotheranostics from bench to bedside. In this review, we will focus on the self-assembly of peptide-photosensitizers and peptide-drugs as well as multicomponent cooperative self-assembly for the fabrication of nanotheranostics that integrate diagnosis and therapeutics for antitumor applications. Emphasis will be placed on building block design, interaction strategies and the potential relationships between their structures and properties, aiming to increase understanding of the critical role of peptide-modulated self-assembly in advancing antitumor supramolecular nanotheranostics. |
资助项目 | National Natural Science Foundation of China[21773248] ; National Natural Science Foundation of China[21802144] ; National Natural Science Fund BRICS STI Framework Programme[51861145304] ; Innovation Research Community Science Fund[21821005] ; Key Research Program of Frontier Sciences of the Chinese Academy of Sciences (CAS)[QYZDB-SSW-JSC034] |
WOS关键词 | AMYLOID-BETA ; NANOPARTICLES ; PROGRESS ; DESIGN ; NANOSTRUCTURES ; HYDROGELS ; DELIVERY ; THERAPY ; CELL ; PHOTOSENSITIZERS |
WOS研究方向 | Research & Experimental Medicine |
语种 | 英语 |
出版者 | IVYSPRING INT PUBL |
WOS记录号 | WOS:000468203100013 |
资助机构 | National Natural Science Foundation of China ; National Natural Science Fund BRICS STI Framework Programme ; Innovation Research Community Science Fund ; Key Research Program of Frontier Sciences of the Chinese Academy of Sciences (CAS) |
内容类型 | 期刊论文 |
源URL | [http://ir.ipe.ac.cn/handle/122111/28357] |
专题 | 中国科学院过程工程研究所 |
通讯作者 | Yan, Xuehai |
作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Ctr Mesosci, Inst Proc Engn, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Jawaharlal Nehru Ctr Adv Sci Res, New Chem Unit, Bioorgan Chem Lab, Jakkur PO, Bengaluru 560064, Karnataka, India 5.Kazan Fed Univ, Inst Fundamental Med & Biol, Bionanotechnol Lab, Kazan 420008, Republic Of Tat, Russia |
推荐引用方式 GB/T 7714 | Li, Shukun,Zou, Qianli,Xing, Ruirui,et al. Peptide-modulated self-assembly as a versatile strategy for tumor supramolecular nanotheranostics[J]. THERANOSTICS,2019,9(11):3249-3261. |
APA | Li, Shukun,Zou, Qianli,Xing, Ruirui,Govindaraju, Thimmaiah,Fakhrullin, Rawil,&Yan, Xuehai.(2019).Peptide-modulated self-assembly as a versatile strategy for tumor supramolecular nanotheranostics.THERANOSTICS,9(11),3249-3261. |
MLA | Li, Shukun,et al."Peptide-modulated self-assembly as a versatile strategy for tumor supramolecular nanotheranostics".THERANOSTICS 9.11(2019):3249-3261. |
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