Chemical components of Hyssopus seravshanicus: antioxidant activity, activations of melanogenesis and tyrosinase, and quantitative determination by UPLC-DAD

doi:10.1080/14786419.2017.1408105

CORC > 新疆理化技术研究所 > 中国科学院新疆理化技术研究所 > 省部共建新疆特有药用资源利用重点实验室

	Chemical components of Hyssopus seravshanicus: antioxidant activity, activations of melanogenesis and tyrosinase, and quantitative determination by UPLC-DAD
	Shomirzoeva, O (Shomirzoeva, Omina)[ 1,2,3 ]; Li, J (Li, Jun)[ 1,2 ]; Numonov, S (Numonov, Sodik)[ 1,2 ]; Mamat, N (Mamat, Nuramina)[ 1,2,3 ]; Shataer, D (Shataer, Dilireba)[ 1,2,3 ]; Lu, XY (Lu, Xueying)[ 1,2 ]; Aisa, HA (Aisa, Haji Abker)[ 1,2 ]
刊名	NATURAL PRODUCT RESEARCH
	2019
卷号	33 期号:6 页码:866-870
关键词	Hyssopus seravshanicus phenolic compounds antioxidant melanogenesis tyrosinase quantitative determination
ISSN号	1478-6419
DOI	10.1080/14786419.2017.1408105
英文摘要	Hyssopus seravshanicus (Dubj.) Pazij has been used as traditional herb and food due to its wide biological properties. Seventeen known compounds were isolated from the ethyl acetate fraction. Their structures were identified by spectroscopic data and comparison with published data. Among them, 14 ones were identified from H. seravshanicus for the first time. DPPH and ABTS radical scavenging activities for crude ethanol extract (CEE), ethyl acetate fraction (EAF), butanol fraction (BF) and compounds 1, 3, 8, 10, 11 and 13 were performed. CEE, compounds 1, 3, 11 and 13 exhibited potent antioxidant activities. Compound 1 was found to increase the melanin content and tyrosinase activity of B16 melanoma cells. Moreover, the quantitative estimation of compound 1 in the ethyl acetate fraction was carried out by UPLC-DAD and the method was validated. This is the first report on the isolation and bioactivity research on the non-valotile components of H. seravshanicus.
WOS记录号	WOS:000466606100016
内容类型	期刊论文
源URL	[http://ir.xjipc.cas.cn/handle/365002/5789]
专题	新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室
通讯作者	Aisa, HA (Aisa, Haji Abker)[ 1,2 ]
作者单位	1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Urumqi, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Shomirzoeva, O ,Li, J ,Numonov, S ,et al. Chemical components of Hyssopus seravshanicus: antioxidant activity, activations of melanogenesis and tyrosinase, and quantitative determination by UPLC-DAD[J]. NATURAL PRODUCT RESEARCH,2019,33(6):866-870.
APA	Shomirzoeva, O .,Li, J .,Numonov, S .,Mamat, N .,Shataer, D .,...&Aisa, HA .(2019).Chemical components of Hyssopus seravshanicus: antioxidant activity, activations of melanogenesis and tyrosinase, and quantitative determination by UPLC-DAD.NATURAL PRODUCT RESEARCH,33(6),866-870.
MLA	Shomirzoeva, O ,et al."Chemical components of Hyssopus seravshanicus: antioxidant activity, activations of melanogenesis and tyrosinase, and quantitative determination by UPLC-DAD".NATURAL PRODUCT RESEARCH 33.6(2019):866-870.