Impact of hypoxia stress on the physiological responses of sea cucumber Apostichopus japonicus：respiration, digestion, immunity and oxidative damage

doi:10.7717/peerj.4651

CORC > 海洋研究所 > 中国科学院海洋研究所 > 海洋生态与环境科学重点实验室

	Impact of hypoxia stress on the physiological responses of sea cucumber Apostichopus japonicus：respiration, digestion, immunity and oxidative damage
	Huo, Da 1,2; Sun, Lina 1; Ru, Xiaoshang 1,2; Zhang, Libin 1; Lin, Chenggang 1; Liu, Shilin 1; Xin, Xiaoke 1,2; Yang, Hongsheng1
刊名	PEERJ
	2018-04-27
卷号	6 期号:0 页码:0
关键词	Echinoderm Anoxia Metabolism Aquatic environment Dissolved oxygen Physiological behavior
ISSN号	2167-8359
DOI	10.7717/peerj.4651
文献子类	Article
英文摘要	Hypoxia is one of the most frequently occurring stressors confronted by industrial cultures of sea cucumber and can cause large economic losses and resource degradation. However, its responsive mechanisms are still lacking. In this paper, the physiological responses of Apostichopus japonicus to oxygen deficiency was illustrated, including induced oxidative response and immune defense and changed digestive enzymes activities. Significantly increased activities of alpha-amylase (AMS), acid phosphatase (ACP), lactate dehydrogenase, catalase, peroxidase, succinate dehydrogenase and higher content of malondialdehyde, and decreased activities of lipase and trypsin (TRY) were observed after hypoxia exposure (dissolved oxygen [DO] 2 mg/L). Expressions of key genes showed that AMS, peptidase, ACP, alkaline phosphatase, lysozyme, heat shock protein 70 and glutathione peroxidase were increased and TRY was decreased under hypoxia. With the decline of the DO level, the decreased tendency of oxygen consumption rates was different in varied weight groups. Moreover, respiratory trees were observed degraded under long-term hypoxia stress, thus leading a negative effect of respiration. These results could help to develop a better understanding of the responsive mechanism of sea cucumber under hypoxia stress and provide a theoretical basis for the prevention of hypoxia risk.
学科主题	Science & Technology - Other Topics
WOS研究方向	Multidisciplinary Sciences
语种	英语
出版者	PEERJ INC
WOS记录号	WOS:000431378500005
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.qdio.ac.cn/handle/337002/157579]
专题	海洋研究所_海洋生态与环境科学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Huo, Da,Sun, Lina,Ru, Xiaoshang,等. Impact of hypoxia stress on the physiological responses of sea cucumber Apostichopus japonicus：respiration, digestion, immunity and oxidative damage[J]. PEERJ,2018,6(0):0.
APA	Huo, Da.,Sun, Lina.,Ru, Xiaoshang.,Zhang, Libin.,Lin, Chenggang.,...&Yang, Hongsheng.(2018).Impact of hypoxia stress on the physiological responses of sea cucumber Apostichopus japonicus：respiration, digestion, immunity and oxidative damage.PEERJ,6(0),0.
MLA	Huo, Da,et al."Impact of hypoxia stress on the physiological responses of sea cucumber Apostichopus japonicus：respiration, digestion, immunity and oxidative damage".PEERJ 6.0(2018):0.