Evolution of Trichocyte Keratin Associated Proteins | |
David M. Irwin1; Dong-Dong Wu2 | |
刊名 | Advances in experimental medicine and biology |
2018 | |
卷号 | 1054期号:*页码:47-56 |
关键词 | Keratin Associated Proteins (Krtap) Hair Phenotypic Evolution Molecular Evolution Concerted Evolution Gene Clusters Mammals |
DOI | 10.1007/978-981-10-8195-8_5 |
英文摘要 | The major components of hair are keratins and keratin associated proteins (KRTAPs). KRTAPs form the interfilamentous matrix between intermediate filament bundles through extensive disulfide bond cross-linking with the numerous cysteine residues in hair keratins. A variable number of approximately100-180 genes compose the KRTAP gene family in mammals. KRTAP gene family members present a typical pattern of concerted evolution, and its evolutionary features are consistent with the evolution of mammalian hair. KRATP genes might be more important in determining the structure of cashmere fibers in domestic mammals like sheep and goats. KRTAP gene variants thus should provide information for improved wool by sheep and goat breeding. |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://159.226.149.26:8080/handle/152453/12354] |
专题 | 昆明动物研究所_进化与发育转录组学 |
通讯作者 | David M. Irwin; Dong-Dong Wu |
作者单位 | 1.Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada 2.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China. |
推荐引用方式 GB/T 7714 | David M. Irwin,Dong-Dong Wu. Evolution of Trichocyte Keratin Associated Proteins[J]. Advances in experimental medicine and biology,2018,1054(*):47-56. |
APA | David M. Irwin,&Dong-Dong Wu.(2018).Evolution of Trichocyte Keratin Associated Proteins.Advances in experimental medicine and biology,1054(*),47-56. |
MLA | David M. Irwin,et al."Evolution of Trichocyte Keratin Associated Proteins".Advances in experimental medicine and biology 1054.*(2018):47-56. |
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