Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan

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	Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan
	Khan A 4,5; Xin Wei X 2,3,4; wangyifen@mail.kib.ac.cn ; : xdluo@mail.kib.ac.cn ; Liu YP 2,4; Dai Z 1,3; Song D 6; Luo XD2,4; Wang YF2,4; Zhao XD 1
刊名	Natural Products and Bioprospecting
	2017
卷号	*期号:1-5 页码:Pubished online
关键词	Apocynaceae Cytotoxicity Pyridine Alkaloids Vinca Major
英文摘要	Three new pyridine type alkaloids, (-)-vinmajpyridines A-C (1-3), along with two known alkaloids, have been isolated from the aerial parts of Vinca major cultivated in Pakistan. Their structures have been elucidated by means of NMR and HRESIMS spectroscopic data. The new alkaloids were evaluated for their cytotoxicity against glioma initiating cell lines (GITC-3# and GITC-18#), glioblastoma cell lines (U-87MG and T98G), and lung cancer cell line A-549, but none of them was active at 20 μg/mL concentration.
语种	英语
资助机构	The authors are grateful to the National Natural Science Foundation of China (81225024) for financial support. ; The authors are grateful to the National Natural Science Foundation of China (81225024) for financial support. ; The authors are grateful to the National Natural Science Foundation of China (81225024) for financial support. ; The authors are grateful to the National Natural Science Foundation of China (81225024) for financial support.
内容类型	期刊论文
源URL	[http://159.226.149.26:8080/handle/152453/11741]
专题	昆明动物研究所_动物模型与人类重大疾病机理重点实验室昆明动物研究所_肿瘤干细胞生物学
通讯作者	wangyifen@mail.kib.ac.cn; : xdluo@mail.kib.ac.cn
作者单位	1.Key Laboratory of Animal Models and Human Disease Mechanisms, Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming 650223, Yunnan, People’s Republic of China 2.Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming 650201, People’s Republic of China 3.University of Chinese Academy of Sciences, Beijing 100049, People’s Republic of China 4.State Key Laboratory of Phytochemistry and Plant Resources of West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People’s Republic of China 5.Department of Chemistry, COMSATS Institute of Information Technology, Abbottabad 22060, Pakistan 6.Yunnan College of Business Management, Kunming 650106, People’s Republic of China
推荐引用方式 GB/T 7714	Khan A,Xin Wei X,wangyifen@mail.kib.ac.cn,et al. Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan[J]. Natural Products and Bioprospecting,2017,*(1-5):Pubished online.
APA	Khan A.,Xin Wei X.,wangyifen@mail.kib.ac.cn.,: xdluo@mail.kib.ac.cn.,Liu YP.,...&Yu HF.(2017).Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan.Natural Products and Bioprospecting,*(1-5),Pubished online.
MLA	Khan A,et al."Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan".Natural Products and Bioprospecting *.1-5(2017):Pubished online.