Recent advances in lipidomics for disease research

doi:10.1002/jssc.201500899

	Recent advances in lipidomics for disease research
	Li, Min 1; Shen, Sensen 1; Liu, Huwei 1; Bai, Yu 1; Yang, Li 1; Shan, Yabing 1,2
刊名	JOURNAL OF SEPARATION SCIENCE
	2016
卷号	39 期号:1 页码:38-50
关键词	Biomarkers Clinical Diagnosis Lipidomics Metabolism
ISSN号	1615-9306
DOI	10.1002/jssc.201500899
文献子类	Review
英文摘要	Lipidomics is an important branch of metabolomics, which aims at the detailed analysis of lipid species and their multiple roles in the living system. In recent years, the development of various analytical methods for effective identification and characterization of lipids has greatly promoted the process of lipidomics. Meanwhile, as many diseases demonstrate a remarkable alteration in lipid profiles compared with that of healthy people, lipidomics has been extensively introduced to disease research. The comprehensive lipid profiling provides a chance to discover novel biomarkers for specific disease. In addition, it plays a crucial role in the study of lipid metabolism, which could illuminate the pathogenesis of diseases. In this review, after brief discussion of analytical methods for lipidomics in clinical research, we focus on the recent advances of lipidomics related to four types of diseases, including cancer, atherosclerosis, diabetes mellitus, and Alzheimer's disease.
WOS关键词	DESORPTION ELECTROSPRAY-IONIZATION ; 2-DIMENSIONAL GAS-CHROMATOGRAPHY ; IMAGING MASS-SPECTROMETRY ; PERITONEAL-DIALYSIS PATIENTS ; FATTY-ACID SYNTHASE ; LC-QTOF-MS ; ALZHEIMERS-DISEASE ; SHOTGUN LIPIDOMICS ; BREAST-CANCER ; HUMAN PLASMA
WOS研究方向	Chemistry
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000368876500004
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/171312]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
通讯作者	Liu, Huwei
作者单位	1.Peking Univ, Beijing Natl Lab Mol Sci, Key Lab Bioorgan Chem & Mol Engn, Minist Educ,Inst Analyt Chem,Coll Chem & Mol Engn, Beijing 100871, Peoples R China 2.Natl Res Ctr Geoanal, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Li, Min,Shen, Sensen,Liu, Huwei,et al. Recent advances in lipidomics for disease research[J]. JOURNAL OF SEPARATION SCIENCE,2016,39(1):38-50.
APA	Li, Min,Shen, Sensen,Liu, Huwei,Bai, Yu,Yang, Li,&Shan, Yabing.(2016).Recent advances in lipidomics for disease research.JOURNAL OF SEPARATION SCIENCE,39(1),38-50.
MLA	Li, Min,et al."Recent advances in lipidomics for disease research".JOURNAL OF SEPARATION SCIENCE 39.1(2016):38-50.