BODIPY-based self-assembled nanoparticles as fluorescence turn-on sensor for the selective detection of zinc in human hair

doi:10.1016/j.bios.2016.05.029

	BODIPY-based self-assembled nanoparticles as fluorescence turn-on sensor for the selective detection of zinc in human hair
	Jia, Ming-Yan 1,2; Wang, Yu 1; Liu, Yang 3; Niu, Li-Ya 3; Feng, Liang 1
刊名	BIOSENSORS & BIOELECTRONICS
	2016-11-15
卷号	85 页码:515-521
关键词	Self-assembled Turn-on Fluorescence Zinc Bodipy
ISSN号	0956-5663
DOI	10.1016/j.bios.2016.05.029
文献子类	Article
英文摘要	Zinc plays important roles in regulating physiological and pathological processes. Regrettably, mild to moderate zinc deficiency is common worldwide. Hair Zn2+ concentration, which reflects a zinc storage status, is useful for tracking trends in zinc status within populations. In this work, we report BODIPY-based self-assembled nanoparticles (NPs) as fluorescence turn-on sensor for the selective sensing of Zn2+ in human hair. The BODIPY monomers (BAN) self-assemble in aqueous medium to form non fluorescent NPs. In the presence of Zn2+ ions, the NPs selectively show an obvious turn-on fluorescence change. This selective response of the NPs allows the determination and quantification of Zn2+ in human hair with a detection limit of 61.3 nM. This study demonstrates that the small molecule self-assembled nanoparticle is a versatile and useful tool, and shows great potential for applications in sensing of important analytes in biological systems. (C) 2016 Elsevier B.V. All rights reserved.
WOS关键词	TRACE-ELEMENTS ; SERUM ; PROBE ; COPPER ; DISEASE ; DESIGN ; WATER ; LEAD ; NEUROBIOLOGY ; DERIVATIVES
WOS研究方向	Biophysics ; Biotechnology & Applied Microbiology ; Chemistry ; Electrochemistry ; Science & Technology - Other Topics
语种	英语
出版者	ELSEVIER ADVANCED TECHNOLOGY
WOS记录号	WOS:000382410100069
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/170084]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
通讯作者	Niu, Li-Ya; Feng, Liang
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Beijing Normal Univ, Beijing 100875, Peoples R China
推荐引用方式 GB/T 7714	Jia, Ming-Yan,Wang, Yu,Liu, Yang,et al. BODIPY-based self-assembled nanoparticles as fluorescence turn-on sensor for the selective detection of zinc in human hair[J]. BIOSENSORS & BIOELECTRONICS,2016,85:515-521.
APA	Jia, Ming-Yan,Wang, Yu,Liu, Yang,Niu, Li-Ya,&Feng, Liang.(2016).BODIPY-based self-assembled nanoparticles as fluorescence turn-on sensor for the selective detection of zinc in human hair.BIOSENSORS & BIOELECTRONICS,85,515-521.
MLA	Jia, Ming-Yan,et al."BODIPY-based self-assembled nanoparticles as fluorescence turn-on sensor for the selective detection of zinc in human hair".BIOSENSORS & BIOELECTRONICS 85(2016):515-521.