Gas Purge Microextraction Coupled with Stable Isotope Labeling-Liquid Chromatography/Mass Spectrometry for the Analysis of Bromophenols in Aquatic Products

	Gas Purge Microextraction Coupled with Stable Isotope Labeling-Liquid Chromatography/Mass Spectrometry for the Analysis of Bromophenols in Aquatic Products
	Zhang, Shijuan ; Yu, Qiuhui ; Sheng, Cuncun ; You, Jinmao
刊名	JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
	2016-12-14
英文摘要	A green, sensitive, and accurate method was developed for the extraction and determination of bromophenols (BPs) from aquatic products by using organic solvent-free gas purge microsyringe extraction (GP-MSE) technique in combination with stable isotope labeling (SIL) strategy. BPs were extracted by NaHCO3 buffer solution, with recoveries varying from 92.0% to 98.5%. The extracted solution was analyzed by SIL strategy, during which analytes and standards were labeled by 10-methyl-acridone-2-sulfonyl chloride (d(0)-MASC) and its deuterated counterpart d(3)-MASC, respectively. The labeling reaction was finished within 10 min with good stability. The liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) sensitivity of BPs was greatly enhanced due to the mass-enhancing property of MASC, while the matrix effect was effectively minimized by the SIL strategy. The limits of detection (LODs) were in the range of 0.10-0.30 mu g/kg, while the limits of quantitations (LOQs) were in the range of 0.32-1.0 mu g/kg. The proposed method also showed great potential in the qualitative analysis of other bromophenols in the absence of standard.
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/6658]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Zhang, Shijuan,Yu, Qiuhui,Sheng, Cuncun,et al. Gas Purge Microextraction Coupled with Stable Isotope Labeling-Liquid Chromatography/Mass Spectrometry for the Analysis of Bromophenols in Aquatic Products[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2016.
APA	Zhang, Shijuan,Yu, Qiuhui,Sheng, Cuncun,&You, Jinmao.(2016).Gas Purge Microextraction Coupled with Stable Isotope Labeling-Liquid Chromatography/Mass Spectrometry for the Analysis of Bromophenols in Aquatic Products.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.
MLA	Zhang, Shijuan,et al."Gas Purge Microextraction Coupled with Stable Isotope Labeling-Liquid Chromatography/Mass Spectrometry for the Analysis of Bromophenols in Aquatic Products".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2016).