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	Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from laminaria japonica
	Wang, Jing1,2; Zhang, Quanbin1; Zhang, Zhongshan1,2; Song, Houfang1,2; Li, Pengcheng1
刊名	International journal of biological macromolecules
	2010
卷号	46期号:1页码:6-12
关键词	Low molecular weight fucoidan Laminaria japonica Antioxidant Anticoagulant
ISSN号	0141-8130
DOI	10.1016/j.ijbiomac.2009.10.015
通讯作者	Zhang, quanbin(qbzhang@ms.qdio.ac.cn)
英文摘要	A low molecular weight fucoidan (dfps), obtained from the brown seaweed laminaria japonica, was separated into three fractions by anion-exchange column chromatography. all three fractions (df1, df2, df3) predominantly contained variety fucose, galactose and sulfate group. the antioxidant and anticoagulant activities of these fractions were investigated. the results showed that all fractions possessed considerable antioxidant activities, df1 was most active. all samples inhibited coagulant in aptt, tt and pt assays obviously. available data presented the content of sulfate group, the molar ratio of sulfate/fucose and sulfate/total sugar, and the molecular weight played an important role on antioxidant and anticoagulant activity. (c) 2009 elsevier b.v. all rights reserved.
WOS关键词	RADICAL SCAVENGING ACTIVITY ; OXIDATIVE STRESS ; CHROMATOGRAPHY ; HEPARIN ; OXYGEN ; TEA ; ROS ; XA
WOS研究方向	Biochemistry & Molecular Biology
WOS类目	Biochemistry & Molecular Biology
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000274971900002
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2409415
专题	中国科学院大学
通讯作者	Zhang, Quanbin
作者单位	1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wang, Jing,Zhang, Quanbin,Zhang, Zhongshan,et al. Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from laminaria japonica[J]. International journal of biological macromolecules,2010,46(1):6-12.
APA	Wang, Jing,Zhang, Quanbin,Zhang, Zhongshan,Song, Houfang,&Li, Pengcheng.(2010).Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from laminaria japonica.International journal of biological macromolecules,46(1),6-12.
MLA	Wang, Jing,et al."Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from laminaria japonica".International journal of biological macromolecules 46.1(2010):6-12.

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