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	Mechanisms regulating oocyte meiotic resumption: roles of mitogen-activated protein kinase
	Liang, Cheng-Guang; Su, You-Qiang; Fan, Heng-Yu; Schatten, Heide; Sun, Qing-Yuan
刊名	Molecular endocrinology
	2007-09-01
卷号	21期号:9页码:2037-2055
ISSN号	0888-8809
DOI	10.1210/m3.2006-0408
通讯作者	Liang, cheng-guang()
英文摘要	Oocyte meiotic maturation is one of the important physiological requirements for species survival. however, little is known about the detailed events occurring during this process. a number of studies have demonstrated that mapk plays a pivotal role in the regulation of meiotic cell cycle progression in oocytes, but controversial findings have been reported in both lower vertebrates and mammals. in this review, we summarized the roles of mapk cascade and related signal pathways in oocyte meiotic reinitiation in both lower vertebrates and mammals. we also tried to reconcile the paradoxical results and highlight the new findings concerning the function of mapk in both oocytes and the surrounding follicular somatic cells. the unresolved questions and future research directions regarding the role of mapk in meiotic resumption are addressed.
WOS关键词	EPIDERMAL-GROWTH-FACTOR ; GERMINAL-VESICLE-BREAKDOWN ; FOLLICLE-STIMULATING-HORMONE ; XENOPUS-LAEVIS OOCYTES ; IN-VITRO MATURATION ; METAPHASE-II ARREST ; SIGNAL-TRANSDUCTION PATHWAY ; ENCLOSED PORCINE OOCYTES ; CELL-CYCLE PROGRESSION ; ISOLATED MOUSE OOCYTES
WOS研究方向	Endocrinology & Metabolism
WOS类目	Endocrinology & Metabolism
语种	英语
出版者	ENDOCRINE SOC
WOS记录号	WOS:000249020200001
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2382886
专题	中国科学院大学
通讯作者	Liang, Cheng-Guang
作者单位	1.Chinese Acad Sci, Inst Zool, State Key Lab Reprod Biol, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100080, Peoples R China 3.Jackson Lab, Bar Harbor, ME 04609 USA 4.Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA 5.Univ Missouri, Dept Vet Pathobiol, Columbia, MO 65211 USA
推荐引用方式 GB/T 7714	Liang, Cheng-Guang,Su, You-Qiang,Fan, Heng-Yu,et al. Mechanisms regulating oocyte meiotic resumption: roles of mitogen-activated protein kinase[J]. Molecular endocrinology,2007,21(9):2037-2055.
APA	Liang, Cheng-Guang,Su, You-Qiang,Fan, Heng-Yu,Schatten, Heide,&Sun, Qing-Yuan.(2007).Mechanisms regulating oocyte meiotic resumption: roles of mitogen-activated protein kinase.Molecular endocrinology,21(9),2037-2055.
MLA	Liang, Cheng-Guang,et al."Mechanisms regulating oocyte meiotic resumption: roles of mitogen-activated protein kinase".Molecular endocrinology 21.9(2007):2037-2055.

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