The JMJD2 members of histone demethylase revisited

	The JMJD2 members of histone demethylase revisited
	Tan, Haidong; Wu, Siguo; Wang, Jinxia; Zhao, Zongbao (Kent)
刊名	molecular biology reports
	2008-12-01
卷号	35 期号:4 页码:551-556
关键词	Eukaryotes Histone demethylation In vivo study JMJD2 Prokaryotes Protein-protein interaction
通讯作者	谭海东
产权排序	1;1
英文摘要	the study of histone lysine demethylases has become very hot recently. many histone demethylases have been reported by different research groups with various techniques. however, how many histone lysine-methylation states can be removed by one specific demethylase and how many demethylases can remove one specific histone lysine-methylation state? it remains a daunting challenge to answer these questions to date. an in-depth discussion on recent results, three important points were provided: (1) some demethylases can remove more histone lysine-methylation states; (2) some prokaryotes might be endowed with histone lysine demethylases although they are devoid of histones; (3) protein-protein interaction provides a valuable framework for a better understanding of the functions of the histone lysine demethylases. all of these will be beneficial to a better understanding of demethylases and suggest how future research can be improved.
WOS标题词	science & technology ; life sciences & biomedicine
类目[WOS]	biochemistry & molecular biology
研究领域[WOS]	biochemistry & molecular biology
关键词[WOS]	androgen-receptor ; functional-characterization ; s-adenosylmethionine ; mammalian-cells ; methyl groups ; h3 ; protein ; family ; lsd1 ; transcription
收录类别	SCI
原文出处	true
语种	英语
WOS记录号	WOS:000261424100010
公开日期	2010-11-30
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/101159]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Tan, Haidong,Wu, Siguo,Wang, Jinxia,et al. The JMJD2 members of histone demethylase revisited[J]. molecular biology reports,2008,35(4):551-556.
APA	Tan, Haidong,Wu, Siguo,Wang, Jinxia,&Zhao, Zongbao .(2008).The JMJD2 members of histone demethylase revisited.molecular biology reports,35(4),551-556.
MLA	Tan, Haidong,et al."The JMJD2 members of histone demethylase revisited".molecular biology reports 35.4(2008):551-556.