Cancer dormancy and criticality from a game theory perspective | |
Wu,Amy1; Liao,David2; Kirilin,Vlamimir3; Lin,Ke-Chih4; Torga,Gonzalo5; Qu,Junle6; Liu,Liyu7; Sturm,James C.4; Pienta,Kenneth5; Austin,Robert3 | |
刊名 | Cancer convergence |
2018-01-22 | |
卷号 | 2期号:1 |
关键词 | Cancer Dormancy Game theory Perturbations Simulation |
ISSN号 | 2366-6196 |
DOI | 10.1186/s41236-018-0008-0 |
通讯作者 | Austin,robert(austin@princeton.edu) |
英文摘要 | Abstractbackgroundthe physics of cancer dormancy, the time between initial cancer treatment and re-emergence after a protracted period, is a puzzle. cancer cells interact with host cells via complex, non-linear population dynamics, which can lead to very non-intuitive but perhaps deterministic and understandable progression dynamics of cancer and dormancy.resultswe explore here the dynamics of host-cancer cell populations in the presence of (1) payoffs gradients and (2) perturbations due to cell migration.conclusionswe determine to what extent the time-dependence of the populations can be quantitively understood in spite of the underlying complexity of the individual agents and model the phenomena of dormancy. |
语种 | 英语 |
出版者 | Springer International Publishing |
WOS记录号 | BMC:10.1186/S41236-018-0008-0 |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/2373541 |
专题 | 物理研究所 |
通讯作者 | Austin,Robert |
作者单位 | 1.Banter AI 2. 3. 4. 5. 6. 7. |
推荐引用方式 GB/T 7714 | Wu,Amy,Liao,David,Kirilin,Vlamimir,et al. Cancer dormancy and criticality from a game theory perspective[J]. Cancer convergence,2018,2(1). |
APA | Wu,Amy.,Liao,David.,Kirilin,Vlamimir.,Lin,Ke-Chih.,Torga,Gonzalo.,...&Austin,Robert.(2018).Cancer dormancy and criticality from a game theory perspective.Cancer convergence,2(1). |
MLA | Wu,Amy,et al."Cancer dormancy and criticality from a game theory perspective".Cancer convergence 2.1(2018). |
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