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Cancer dormancy and criticality from a game theory perspective
Wu,Amy1; Liao,David2; Kirilin,Vlamimir3; Lin,Ke-Chih4; Torga,Gonzalo5; Qu,Junle6; Liu,Liyu7; Sturm,James C.4; Pienta,Kenneth5; Austin,Robert3
刊名Cancer convergence
2018-01-22
卷号2期号:1
关键词Cancer Dormancy Game theory Perturbations Simulation
ISSN号2366-6196
DOI10.1186/s41236-018-0008-0
通讯作者Austin,robert(austin@princeton.edu)
英文摘要Abstractbackgroundthe physics of cancer dormancy, the time between initial cancer treatment and re-emergence after a protracted period, is a puzzle. cancer cells interact with host cells via complex, non-linear population dynamics, which can lead to very non-intuitive but perhaps deterministic and understandable progression dynamics of cancer and dormancy.resultswe explore here the dynamics of host-cancer cell populations in the presence of (1) payoffs gradients and (2) perturbations due to cell migration.conclusionswe determine to what extent the time-dependence of the populations can be quantitively understood in spite of the underlying complexity of the individual agents and model the phenomena of dormancy.
语种英语
出版者Springer International Publishing
WOS记录号BMC:10.1186/S41236-018-0008-0
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2373541
专题物理研究所
通讯作者Austin,Robert
作者单位1.Banter AI
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推荐引用方式
GB/T 7714
Wu,Amy,Liao,David,Kirilin,Vlamimir,et al. Cancer dormancy and criticality from a game theory perspective[J]. Cancer convergence,2018,2(1).
APA Wu,Amy.,Liao,David.,Kirilin,Vlamimir.,Lin,Ke-Chih.,Torga,Gonzalo.,...&Austin,Robert.(2018).Cancer dormancy and criticality from a game theory perspective.Cancer convergence,2(1).
MLA Wu,Amy,et al."Cancer dormancy and criticality from a game theory perspective".Cancer convergence 2.1(2018).
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