| Fowl adenovirus serotype 4: epidemiology, pathogenesis, diagnostic detection, and vaccine strategies | |
| Li, P. H.1,2; Zheng, P. P.1,3; Zhang, T. F.1,3; Wen, G. Y.1,3; Shao, H. B.1,3; Luo, Q. P.1,3 | |
| 刊名 | Poultry science
 |
| 2017-08-01 | |
| 卷号 | 96期号:8页码:2630-2640 |
| 关键词 | Diagnosis Epidemiology Fadv-4 Pathogenesis Vaccine |
| ISSN号 | 0032-5791 |
| DOI | 10.3382/ps/pex087 |
| 通讯作者 | Luo, q. p.(qingping0524@163.com) |
| 英文摘要 | Fowl adenovirus (fadv) serotype-4 is highly pathogenic for chickens, especially for broilers aged 3 to 5 wk, and it has emerged as one of the foremost causes of economic losses to the poultry industry in the last 30 years. the liver is a major target organ of fadv-4 infections, and virus-infected chickens usually show symptoms of hydropericardium syndrome. the virus is very contagious, and it is spread both vertically and horizontally. it can be isolated from infected liver homogenates and detected by several laboratory diagnostic methods (including an agar gel immunodif-fusion test, indirect immunofluorescence assays, counterimmunoelectrophoresis, enzyme-linked immunosorbent assays, restriction endonuclease analyses, polymerase chain reaction (pcr), real-time pcr, and high-resolution melting-curve analyses). although inactivated vaccines have been deployed widely to control the disease, attenuated live vaccines and subunit vaccines also have been developed, and they are more attractive vaccine candidates. this article provides a comprehensive review of fadv-4, including its epidemiology, pathogenesis, diagnostic detection, and vaccine strategies. |
| WOS关键词 | INCLUSION-BODY HEPATITIS ; POLYMERASE-CHAIN-REACTION ; RESTRICTION ENZYME ANALYSIS ; LINKED-IMMUNOSORBENT-ASSAY ; IN-SITU HYBRIDIZATION ; TRANSMISSION ELECTRON-MICROSCOPY ; MELTING-CURVE ANALYSIS ; TIME PCR ASSAY ; HYDROPERICARDIUM SYNDROME ; BROILER-CHICKENS |
| WOS研究方向 | Agriculture |
| WOS类目 | Agriculture, Dairy & Animal Science |
| 语种 | 英语 |
| 出版者 | OXFORD UNIV PRESS |
| WOS记录号 | WOS:000406764500016 |
| 内容类型 | 期刊论文 |
| URI标识 | http://www.corc.org.cn/handle/1471x/2373369 |
| 专题 | 武汉病毒研究所 |
| 通讯作者 | Luo, Q. P. |
| 作者单位 | 1.Hubei Acad Agr Sci, Inst Anim Husb & Vet Sci, Minist Agr, Key Lab Prevent & Control Agents Anim Bacteriosis, Special 1, Wuhan 430064, Hubei, Peoples R China 2.Chinese Acad Sci, Wuhan Inst Virol, Key Lab Special Pathogens & Biosafety, Wuhan, Hubei, Peoples R China 3.Hubei Acad Agr Sci, Inst Anim Husb & Vet Sci, Hubei Key Lab Anim Embryo & Mol Breeding, Special 1, Wuhan 430064, Hubei, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, P. H.,Zheng, P. P.,Zhang, T. F.,et al. Fowl adenovirus serotype 4: epidemiology, pathogenesis, diagnostic detection, and vaccine strategies[J]. Poultry science,2017,96(8):2630-2640. |
| APA | Li, P. H.,Zheng, P. P.,Zhang, T. F.,Wen, G. Y.,Shao, H. B.,&Luo, Q. P..(2017).Fowl adenovirus serotype 4: epidemiology, pathogenesis, diagnostic detection, and vaccine strategies.Poultry science,96(8),2630-2640. |
| MLA | Li, P. H.,et al."Fowl adenovirus serotype 4: epidemiology, pathogenesis, diagnostic detection, and vaccine strategies".Poultry science 96.8(2017):2630-2640. |
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