Synthesized different derivatives of low molecular fucoidan extracted from Laminaria japonica and their potential antioxidant activity in vitro

doi:10.1016/j.ijbiomac.2009.02.001

	Synthesized different derivatives of low molecular fucoidan extracted from Laminaria japonica and their potential antioxidant activity in vitro
	Wang, Jing1,2 ; Wang, Feng3 ; Zhang, Quanbin 1; Zhang, Zhongshan 1,2; Shi, Xuelian 1,2; Li, Pengcheng1
刊名	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
	2009-06-01
卷号	44 期号:5 页码:379-384
关键词	Low Molecular Fucoidan Derivatives Antioxidant Activity
ISSN号	0141-8130
DOI	10.1016/j.ijbiomac.2009.02.001
文献子类	Article
英文摘要	Six low molecular fucoidan (DFPS) derivatives were synthesized successfully, and their potential antioxidant activities were investigated employing various established in vitro systems. All DFPS derivatives possessed considerable antioxidant activity, and had stronger antioxidant ability than DFPS in certain tests. The benzoylated DFPS (PHDF) showed strongest scavenging activity on superoxide, hydroxyl and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, however, DFPS exhibited greatest reducing power. Available data suggested that substituted groups of DFPS played an important role on antioxidant activity, and the mechanism on influence the antioxidant activity of samples of substituted group was indicated. (C) 2009 Elsevier B.V. All rights reserved.; Six low molecular fucoidan (DFPS) derivatives were synthesized successfully, and their potential antioxidant activities were investigated employing various established in vitro systems. All DFPS derivatives possessed considerable antioxidant activity, and had stronger antioxidant ability than DFPS in certain tests. The benzoylated DFPS (PHDF) showed strongest scavenging activity on superoxide, hydroxyl and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, however, DFPS exhibited greatest reducing power. Available data suggested that substituted groups of DFPS played an important role on antioxidant activity, and the mechanism on influence the antioxidant activity of samples of substituted group was indicated. (C) 2009 Elsevier B.V. All rights reserved.
学科主题	Biochemistry & Molecular Biology
URL标识	查看原文
语种	英语
WOS记录号	WOS:000266712500001
公开日期	2010-12-22
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/3493]
专题	海洋研究所_海洋生物技术研发中心海洋研究所_海洋生态与环境科学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Wei Fang Med Univ, Pharmaceut Lab, Weifang 261053, Peoples R China
推荐引用方式 GB/T 7714	Wang, Jing,Wang, Feng,Zhang, Quanbin,et al. Synthesized different derivatives of low molecular fucoidan extracted from Laminaria japonica and their potential antioxidant activity in vitro[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2009,44(5):379-384.
APA	Wang, Jing,Wang, Feng,Zhang, Quanbin,Zhang, Zhongshan,Shi, Xuelian,&Li, Pengcheng.(2009).Synthesized different derivatives of low molecular fucoidan extracted from Laminaria japonica and their potential antioxidant activity in vitro.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,44(5),379-384.
MLA	Wang, Jing,et al."Synthesized different derivatives of low molecular fucoidan extracted from Laminaria japonica and their potential antioxidant activity in vitro".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 44.5(2009):379-384.