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	Isolation, Characterization, and Antioxidant Activity of Bromophenols of the Marine Red Alga Rhodomela confervoides
	Li, Ke1; Li, Xiao-Ming1; Gloer, James B.2; Wang, Bin-Gui1
刊名	JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
	2011-09-28
卷号	59期号:18页码:9916-9921
关键词	Marine Alga Rhodomela Confervoides Bromophenol Radical Scavenging Activity Dpph Abts
ISSN号	0021-8561
DOI	10.1021/jf2022447
文献子类	Article
英文摘要	A total of 19 naturally occurring bromophenols, with six new and 13 known structures, were isolated and identified from the methanolic extract of the marine red alga Rhodomela confervoides. The new compounds were identified by spectroscopic methods as 3,4-dibromo-5-((methylsulfonyl)methyl)benzene-1,2-diol (1), 3,4-dibromo-5-((2,3-dihydroxypropoxy)methyl)benzene-1,2-diol (2), 5-(aminomethyl)-3,4-dibromobenzene-1,2-diol (3), 2-(2,3-dibromo-4,5-dihydroxyphenyl)acetic acid (4), 2-methoxy-3-bromo-5-hydroxymethylphenol (5), and (E)-4-(2-bromo-4,5-dihydroxyphenyl)but-3-en-2-one (6). Each compound was evaluated for free radical scavenging activity against DPPH (a,alpha-diphenyl-beta-dipicrylhydrazyl) and ABTS [2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid)diammonium salt] radicals. Most of them exhibited potent activities stronger than or comparable to the positive controls butylated hydroxytoluene (BHT) and ascorbic acid. The results from this study suggest that R. confervoides is an excellent source of natural antioxidants, and inclusion of these antioxidant-rich algal components would likely help prevent the oxidative deterioration of food.; A total of 19 naturally occurring bromophenols, with six new and 13 known structures, were isolated and identified from the methanolic extract of the marine red alga Rhodomela confervoides. The new compounds were identified by spectroscopic methods as 3,4-dibromo-5-((methylsulfonyl)methyl)benzene-1,2-diol (1), 3,4-dibromo-5-((2,3-dihydroxypropoxy)methyl)benzene-1,2-diol (2), 5-(aminomethyl)-3,4-dibromobenzene-1,2-diol (3), 2-(2,3-dibromo-4,5-dihydroxyphenyl)acetic acid (4), 2-methoxy-3-bromo-5-hydroxymethylphenol (5), and (E)-4-(2-bromo-4,5-dihydroxyphenyl)but-3-en-2-one (6). Each compound was evaluated for free radical scavenging activity against DPPH (a,alpha-diphenyl-beta-dipicrylhydrazyl) and ABTS [2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid)diammonium salt] radicals. Most of them exhibited potent activities stronger than or comparable to the positive controls butylated hydroxytoluene (BHT) and ascorbic acid. The results from this study suggest that R. confervoides is an excellent source of natural antioxidants, and inclusion of these antioxidant-rich algal components would likely help prevent the oxidative deterioration of food.
学科主题	Agriculture ; Chemistry ; Food Science & Technology
URL标识	查看原文
语种	英语
WOS记录号	WOS:000295059100024
公开日期	2012-07-03
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/11888]
专题	海洋研究所_实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Iowa, Dept Chem, Iowa City, IA 52242 USA
推荐引用方式 GB/T 7714	Li, Ke,Li, Xiao-Ming,Gloer, James B.,et al. Isolation, Characterization, and Antioxidant Activity of Bromophenols of the Marine Red Alga Rhodomela confervoides[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2011,59(18):9916-9921.
APA	Li, Ke,Li, Xiao-Ming,Gloer, James B.,&Wang, Bin-Gui.(2011).Isolation, Characterization, and Antioxidant Activity of Bromophenols of the Marine Red Alga Rhodomela confervoides.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,59(18),9916-9921.
MLA	Li, Ke,et al."Isolation, Characterization, and Antioxidant Activity of Bromophenols of the Marine Red Alga Rhodomela confervoides".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 59.18(2011):9916-9921.

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