Reviews on The Immunological Function of Tetraspanins

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	Reviews on The Immunological Function of Tetraspanins
	Gui Lang; Wang Bing; Li Fu-Hua; Xiang Jian-Hai
刊名	PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
	2008-11-01
卷号	35 期号:11 页码:1231-1238
关键词	Tetraspanins Immunity Virus Transmembrane 4 Superfamily Invertebrate
ISSN号	1000-3282
文献子类	Review
英文摘要	Tetraspanins belongs to the transmembrane 4 superfamily(TM4SF). They can be as a bridge to connect the proteins outside or inside the cell membrane. A tetraspanins web is formed by the tetraspnins-proteins complex, and the web is believed to involve in fundamental functions of immunity system, and consequnently, signaling between cells and inside cells, regulating cell activation and adhesion, participating in the identification and infection of some virus. As a family of conservative transmembrane proteins, tetraspanins play multiplex roles in invertebrate. It was described how tetraspanin microdomains might have functions in the immune system, and how they contact with virus. In addition, the important role of tetraspanins in the innate immune system of invertebrate were discussed.; Tetraspanins belongs to the transmembrane 4 superfamily(TM4SF). They can be as a bridge to connect the proteins outside or inside the cell membrane. A tetraspanins web is formed by the tetraspnins-proteins complex, and the web is believed to involve in fundamental functions of immunity system, and consequnently, signaling between cells and inside cells, regulating cell activation and adhesion, participating in the identification and infection of some virus. As a family of conservative transmembrane proteins, tetraspanins play multiplex roles in invertebrate. It was described how tetraspanin microdomains might have functions in the immune system, and how they contact with virus. In addition, the important role of tetraspanins in the innate immune system of invertebrate were discussed.
学科主题	Biochemistry & Molecular Biology ; Biophysics
语种	英语
WOS记录号	WOS:000261290200003
公开日期	2010-12-24
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/5565]
专题	海洋研究所_实验海洋生物学重点实验室
作者单位	Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Gui Lang,Wang Bing,Li Fu-Hua,et al. Reviews on The Immunological Function of Tetraspanins[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2008,35(11):1231-1238.
APA	Gui Lang,Wang Bing,Li Fu-Hua,&Xiang Jian-Hai.(2008).Reviews on The Immunological Function of Tetraspanins.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,35(11),1231-1238.
MLA	Gui Lang,et al."Reviews on The Immunological Function of Tetraspanins".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 35.11(2008):1231-1238.