Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives.

	Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives.
	Yang, Dong-Qiong; Chen, Zhao-Rong; Chen, Duo-Zhi; Hao, Xiao-Jiang; Li, Shun-Lin
刊名	Natural products and bioprospecting
	2018
卷号	8 期号:3 页码:189-197
ISSN号	2192-2195
英文摘要	Fifteen known amaryllidaceae alkaloids were isolated from the bulbs of Lycoris radiata. Some of the compounds and lycoricidine derivatives had been screened for the activities against tobacco mosaic virus (TMV) by the conventional half-leaf method. Lycoricidine derivatives were also carried out the assay of effect on systemic infection of TMV by western-blot and RT-PCR analysis. The tested compounds showed moderate inactivation effect, whereas the lycoricidine derivatives showed good protective effect. The protective inhibitory activity of compounds L1 (N-methyl-2,3,4-trimethoxylycoricidine) (60.8%) and L3 (N-methyl-2-methoxy-3,4-acetonidelycoricidine) (62.0%) was almost similar to the positive control, Ningnanmycin (66.4%). RT-PCR and Western-blot analysis displayed that compounds L1, L3, L5 (N-allyl-2,3,4-triallyloxylycoricidine) exhibited antiviral activity, which was evidenced by reducing TMV-CP gene replication and TMV-CP protein expression. Additionally, defensive enzyme activities confirmed that compound L1 could increase the activity of PAL, POD, SOD to improve disease resistance of tobacco.
语种	英语
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/64810]
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Yang, Dong-Qiong,Chen, Zhao-Rong,Chen, Duo-Zhi,et al. Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives.[J]. Natural products and bioprospecting,2018,8(3):189-197.
APA	Yang, Dong-Qiong,Chen, Zhao-Rong,Chen, Duo-Zhi,Hao, Xiao-Jiang,&Li, Shun-Lin.(2018).Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives..Natural products and bioprospecting,8(3),189-197.
MLA	Yang, Dong-Qiong,et al."Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives.".Natural products and bioprospecting 8.3(2018):189-197.