| MR/ fluorescence dual-modality image-guided multifunctional albumin nanoassembies for sonodynamic therapy of glioma | |
| Wan Qian; Zou Chao; Chen Mengjie; Sheng Zonghai; Zhou Jun; Zhu Yanwen; Zheng Hairong; Liu Xin | |
| 2018 | |
| 会议日期 | 2018 |
| 会议地点 | Paris Expo Porte de Versailles Paris, France |
| 英文摘要 | Sonodynamic therapy (SDT) is a non-invasive and effective therapeutic modality for solid cancerous tumors. In this study, to improve the effectiveness of SDT, we fabricated a high-performance multifunctional albumin nanoassembies (HSA-Ce6-Mn NCs) having higher cell uptake efficiency and the tumor accumulation. It also exhibited an excellent ability of MR/ fluorescence (FL) dual-modality imaging so that glioma margin and HSA-Ce6-Mn NCs metabolism could be clearly visualized. The SDT has been demonstrated for suppressing the tumor growth in-vivo under a MRI-guided FUS system and it is highly expected to have a great potential in clinical translation. |
| URL标识 | 查看原文 |
| 内容类型 | 会议论文 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14546]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 推荐引用方式 GB/T 7714 | Wan Qian,Zou Chao,Chen Mengjie,et al. MR/ fluorescence dual-modality image-guided multifunctional albumin nanoassembies for sonodynamic therapy of glioma[C]. 见:. Paris Expo Porte de Versailles Paris, France. 2018. |
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