3D Printing of Lotus Root-Like Biomimetic Materials for Cell Delivery and Tissue Regeneration

doi:10.1002/advs.201700401

	3D Printing of Lotus Root-Like Biomimetic Materials for Cell Delivery and Tissue Regeneration
	Feng, Chun 1; Zhang, Wenjie 2; Deng, Cuijun 1; Li, Guanglong 2; Chang, Jiang ; Zhang, Zhiyuan 3; Jiang, Xinquan 2; Wu, Chengtie
刊名	ADVANCED SCIENCE
	2017
卷号	4 期号:12
ISSN号	2198-3844
DOI	10.1002/advs.201700401
英文摘要	Biomimetic materials have drawn more and more attention in recent years. Regeneration of large bone defects is still a major clinical challenge. In addition, vascularization plays an important role in the process of large bone regeneration and microchannel structure can induce endothelial cells to form rudimentary vasculature. In recent years, 3D printing scaffolds are major materials for large bone defect repair. However, these traditional 3D scaffolds have low porosity and nonchannel structure, which impede angiogenesis and osteogenesis. In this study, inspired by the microstructure of natural plant lotus root, biomimetic materials with lotus root-like structures are successfully prepared via a modified 3D printing strategy. Compared with traditional 3D materials, these biomimetic materials can significantly improve in vitro cell attachment and proliferation as well as promote in vivo osteogenesis, indicating potential application for cell delivery and bone regeneration.
WOS记录号	WOS:000418385800015
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/26622]
专题	中国科学院上海硅酸盐研究所
作者单位	1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China 2.Univ Chinese Acad Sci, 19 Yuquan Rd, Beijing 100049, Peoples R China 3.Shanghai Jiao Tong Univ, Dept Prosthodont, Oral Bioengn & Regenerat Med Lab, Shanghai Key Lab Stomatol,Peoples Hosp 9,Sch Med, 639 Zhizaoju Rd, Shanghai 200011, Peoples R China 4.Shanghai Jiao Tong Univ, Peoples Hosp 9, Sch Med, Oral & Maxillofacial Surg, 639 Zhizaoju Rd, Shanghai 200011, Peoples R China
推荐引用方式 GB/T 7714	Feng, Chun,Zhang, Wenjie,Deng, Cuijun,et al. 3D Printing of Lotus Root-Like Biomimetic Materials for Cell Delivery and Tissue Regeneration[J]. ADVANCED SCIENCE,2017,4(12).
APA	Feng, Chun.,Zhang, Wenjie.,Deng, Cuijun.,Li, Guanglong.,Chang, Jiang.,...&Wu, Chengtie.(2017).3D Printing of Lotus Root-Like Biomimetic Materials for Cell Delivery and Tissue Regeneration.ADVANCED SCIENCE,4(12).
MLA	Feng, Chun,et al."3D Printing of Lotus Root-Like Biomimetic Materials for Cell Delivery and Tissue Regeneration".ADVANCED SCIENCE 4.12(2017).