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	Fluoroquinolones in the Wenyu River catchment, China: Occurrence simulation and risk assessment
	Hao X. W.; Cao, Y.; Zhang, L.; Zhang, Y. Y.; Liu, J. G.
	2015
关键词	Pharmaceuticals and personal care products (PPCPs) Fluoroquinolones GREAT-ER Risk assessment sewage-treatment plants tandem mass-spectrometry personal care products water treatment plants the-drain chemicals waste-water great-er aquatic environment south china human pharmaceuticals
英文摘要	Concern is increasing regarding the environmental impact of the high usage rate and intensive release of antibiotics used for human and animal therapy in major urban areas of China. In the present study, regional environmental distribution simulations and risk assessments for 3 commonly used fluoroquinolones in the Wenyu River catchment were conducted using a typical catchment model widely used in Europe. The fluoroquinolone antibiotics investigated (ofloxacin, norfloxacin, and ciprofloxacin) are consumed at high levels for personal health care in China. These antibiotics were simulated in the aquatic environment of the Wenyu River catchment across the Beijing City area for annual average concentrations, with regional predicted environmental concentrations (PECs) of approximately 711ng/L, 55.3ng/L, and 22.2ng/L and local PECs up to 1.8 mu g/L, 116ng/L, and 43ng/L, respectively. Apart from hydrological conditions, the concentrations of fluoroquinolones were associated closely with the sewage treatment plants (STPs) and their serving population, as well as hospital distributions. The presence of these fluoroquinolones in the catchment area of the present study showed significant characteristics of the occurrence of pharmaceuticals in the aquatic environment in an urban river, with typical down-the-drain chemicals. Significantly high concentrations of specific antibiotics indicated non-negligible risks caused by the intensive use in the local aquatic environment in a metropolitan area, particularly ofloxacin in upstream Shahe Reservoir, middle stream and downstream Qing River, and Liangma River to the Ba River segment. Specific treatment measures for these pharmaceuticals and personal care products in STPs are required for such metropolitan areas. Environ Toxicol Chem 2015;34:2764-2770. (c) 2015 SETAC
出处	Environmental Toxicology and Chemistry
卷	34
期	12
页	2764-2770
语种	英语
ISSN号	0730-7268
DOI标识	10.1002/etc.3158
内容类型	SCI/SSCI论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/43531]
专题	地理科学与资源研究所_历年回溯文献
推荐引用方式 GB/T 7714	Hao X. W.,Cao, Y.,Zhang, L.,et al. Fluoroquinolones in the Wenyu River catchment, China: Occurrence simulation and risk assessment. 2015.

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