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	Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia
	Liu, Xiaochuan; Wang, Beilei; Wang, Junjie; Zhang, Yicong; Jiang, Zongru; Wu, Hong; Liu, Xuesong; Chen, Cheng; Hu, Chen; Wang, Wenliang
刊名	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
	2018
卷号	Vol.160页码:61-81
关键词	ABL kinase Kinase inhibitor ABL mutant CML
ISSN号	0223-5234
URL标识	查看原文
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2201192
专题	安徽大学
作者单位	1.Chinese Acad Sci, Hefei Inst Phys Sci, Key Lab High Magnet Field & Ion Beam Phys Biol, High Field Magnet Lab, Hefei 230031, Anhui, Peoples R China 2.Chinese Acad Sci, Hefei Inst Phys Sci, Inst Technol Innovat, Precis Targeted Therapy Discovery Ctr, Hefei 230088, Anhui, Peoples R China 3.Anhui Med Univ, Affiliated Hosp 1, Dept Hematol, Hefei 230022, Anhui, Peoples R China 4.Univ Sci & Technol China, Hefei 230036, Anhui, Peoples R China 5.Precis Med Res Lab Anhui Prov, Hefei 230088, Anhui, Peoples R China 6.Anhui Univ, Inst Phys Sci & Informat Technol, Hefei 230601, Anhui, Peoples R China
推荐引用方式 GB/T 7714	Liu, Xiaochuan,Wang, Beilei,Wang, Junjie,et al. Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,2018,Vol.160:61-81.
APA	Liu, Xiaochuan.,Wang, Beilei.,Wang, Junjie.,Zhang, Yicong.,Jiang, Zongru.,...&Wang, Wenliang.(2018).Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,Vol.160,61-81.
MLA	Liu, Xiaochuan,et al."Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia".EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY Vol.160(2018):61-81.

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