| Cu-t-1 sensor for versatile analysis | |
| Dong, Mingling1,2,3,4,5; Zheng, Wenshu4,5; Chen, Yiping4,5; Ran, Bei1,2,3,4,5; Qian, Zhiyong1,2,3; Jiang, Xingyu4,5,6 | |
| 刊名 | Analytical chemistry
 |
| 2018-02-20 | |
| 卷号 | 90期号:4页码:2833-2838 |
| ISSN号 | 0003-2700 |
| DOI | 10.1021/acs.analchem.7b04971 |
| 通讯作者 | Chen, yiping(chenyp@nanoctr.cn) ; Qian, zhiyong(anderson-qian@163.com) ; Jiang, xingyu(xingyujiang@nanoctr.cn) |
| 英文摘要 | Conventional magnetic sensors usually employ fe-based magnetic materials as signal probes. in this work, we find that cu(ii) is also a useful longitudinal relaxation time (t-1) signal-based magnetic probe. we adopt bathocuproinedisulfonic acid disodium salt hydrate (bcs) to chelate cu(i) and form a stable cu(i) bcs complex in aqueous solution and find the significant difference in the t-1 value of water protons between cu(ii) aqueous solution and cu(i) bcs complex aqueous solution. redox reaction can convert cu(ii) to cu(i) followed by the complexation of bcs, which results in apparent change of t-1 that can serve as magnetic signal readout, which is the basis of this cu-t-1 sensor. many redox reactions between cu(ii) and cu(i) allow this cu-t-1 sensor to not only realize "one-step mode" assay such as ascorbic acid, protein, and alkaline phosphatase but also enable "multi-step mode" immunoassay, such as biomacromolecules and small molecules. this cu-t-1 sensor employs cu ion as signal readout, providing an alternative tool for biochemical analysis. |
| WOS关键词 | PROTON RELAXATION-TIMES ; CLICK CHEMISTRY ; PARAMAGNETIC SOLUTIONS ; ASCORBIC-ACID ; ONE-STEP ; NANOPARTICLES ; COPPER ; IMMUNOASSAY ; MECHANISM ; PATHOGENS |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Analytical |
| 语种 | 英语 |
| 出版者 | AMER CHEMICAL SOC |
| WOS记录号 | WOS:000426143100061 |
| 内容类型 | 期刊论文 |
| URI标识 | http://www.corc.org.cn/handle/1471x/2177982 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Chen, Yiping; Qian, Zhiyong; Jiang, Xingyu |
| 作者单位 | 1.Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China 2.Sichuan Univ, West China Hosp, Canc Ctr, Chengdu 610041, Sichuan, Peoples R China 3.Collaborat Innovat Ctr, Chengdu 610041, Sichuan, Peoples R China 4.Natl Ctr NanoSci & Technol, Beijing Engn Res Ctr BioNanotechnol, 11 Zhongguancun Beiyitiao, Beijing 100190, Peoples R China 5.Natl Ctr NanoSci & Technol, CAS Key Lab Biomed Effects Nanomat & Nanosafety, CAS Ctr Excellence Nanosci, 11 Zhongguancun Beiyitiao, Beijing 100190, Peoples R China 6.Univ Chinese Acad Sci, 19 A Yuquan Rd, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Dong, Mingling,Zheng, Wenshu,Chen, Yiping,et al. Cu-t-1 sensor for versatile analysis[J]. Analytical chemistry,2018,90(4):2833-2838. |
| APA | Dong, Mingling,Zheng, Wenshu,Chen, Yiping,Ran, Bei,Qian, Zhiyong,&Jiang, Xingyu.(2018).Cu-t-1 sensor for versatile analysis.Analytical chemistry,90(4),2833-2838. |
| MLA | Dong, Mingling,et al."Cu-t-1 sensor for versatile analysis".Analytical chemistry 90.4(2018):2833-2838. |
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