QQ客服 官方微博 反馈留言

	Self-assembled peptide-based nanomaterials for biomedical imaging and therapy
	Qi, Guo-Bin; Gao, Yu-Juan; Wang, Lei; Wang, Hao
刊名	Advanced materials
	2018-05-29
卷号	30期号:22页码:34
关键词	Bioimaging Drug delivery Nanomaterials Peptides Self-assembly
ISSN号	0935-9648
DOI	10.1002/adma.201703444
通讯作者	Wang, lei(wanglei@nanoctr.cn) ; Wang, hao(wanghao@nanoctr.cn)
英文摘要	Peptide-based materials are one of the most important biomaterials, with diverse structures and functionalities. over the past few decades, a self-assembly strategy is introduced to construct peptide-based nanomaterials, which can form well-controlled superstructures with high stability and multivalent effect. more recently, peptide-based functional biomaterials are widely utilized in clinical applications. however, there is no comprehensive review article that summarizes this growing area, from fundamental research to clinic translation. in this review, the recent progress of peptide-based materials, from molecular building block peptides and self-assembly driving forces, to biomedical and clinical applications is systematically summarized. ex situ and in situ constructed nanomaterials based on functional peptides are presented. the advantages of intelligent in situ construction of peptide-based nanomaterials in vivo are emphasized, including construction strategy, nanostructure modulation, and biomedical effects. this review highlights the importance of self-assembled peptide nanostructures for nanomedicine and can facilitate further knowledge and understanding of these nanosystems toward clinical translation.
WOS关键词	AGGREGATION-INDUCED EMISSION ; FDA DRUG APPROVALS ; ENZYME-RESPONSIVE NANOPARTICLES ; RESONANCE ENERGY-TRANSFER ; ELASTIN-LIKE POLYPEPTIDE ; BREAST-CANCER CELLS ; ACTIVITY IN-VIVO ; LIGHT-UP PROBE ; PHAGE DISPLAY ; SMALL MOLECULES
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS类目	Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000434034100034
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2177534
专题	高能物理研究所
通讯作者	Wang, Lei; Wang, Hao
作者单位	Natl Ctr Nanosci & Technol NCNST, CAS Ctr Excellence Nanosci, CAS Key Lab Biol Effects Nanomat & Nanosafety, 11 Beiyitiao, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Qi, Guo-Bin,Gao, Yu-Juan,Wang, Lei,et al. Self-assembled peptide-based nanomaterials for biomedical imaging and therapy[J]. Advanced materials,2018,30(22):34.
APA	Qi, Guo-Bin,Gao, Yu-Juan,Wang, Lei,&Wang, Hao.(2018).Self-assembled peptide-based nanomaterials for biomedical imaging and therapy.Advanced materials,30(22),34.
MLA	Qi, Guo-Bin,et al."Self-assembled peptide-based nanomaterials for biomedical imaging and therapy".Advanced materials 30.22(2018):34.

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。