Controlled cell patterning on bioactive surfaces with special wettability | |
Zhou, Xiaofeng1; Li, Jianqian2; Sun, Hongyan3; Hu, Yi4; Che, Lufeng1,5; Wang, Zuankai2 | |
刊名 | Journal of bionic engineering |
2017-07-01 | |
卷号 | 14期号:3页码:440-447 |
关键词 | Cell patterning Wettability Superhydrophilic Surface chemistry Circulating tumor cells |
ISSN号 | 1672-6529 |
DOI | 10.1016/s1672-6529(16)60409-2 |
通讯作者 | Che, lufeng(lfche@zju.edu.cn) ; Wang, zuankai(zuanwang@cityu.edu.hk) |
英文摘要 | The ability to control cell patterning on artificial substrates with various physicochemical properties is of essence for important implications in cytology and biomedical fields. despite extensive progress, the ability to control the cell-surface interaction is complicated by the complexity in the physiochemical features of bioactive surfaces. in particular, the manifestation of special wettability rendered by the combination of surface roughness and surface chemistry further enriches the cell-surface interaction. herein we investigated the cell adhesion behaviors of circulating tumor cells (ctcs) on topographically patterned but chemically homogeneous surfaces. harnessing the distinctive cell adhesion on surfaces with different topography, we further explored the feasibility of controlled cell patterning using periodic lattices of alternative topographies. we envision that our method provides a designer's toolbox to manage the extracellular environment. |
WOS关键词 | CIRCULATING TUMOR-CELLS ; CANCER-CELLS ; EFFICIENT CAPTURE ; NANOWIRE ARRAYS ; BREAST-CANCER ; RELEASE ; NANOPARTICLES ; INTERFACES ; BACTERIA ; ADHESION |
WOS研究方向 | Engineering ; Materials Science ; Robotics |
WOS类目 | Engineering, Multidisciplinary ; Materials Science, Biomaterials ; Robotics |
语种 | 英语 |
出版者 | SCIENCE PRESS |
WOS记录号 | WOS:000406572300002 |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/2176964 |
专题 | 高能物理研究所 |
通讯作者 | Che, Lufeng; Wang, Zuankai |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Microsyst & Informat Technol, Sci & Technol Microsyst Lab, Shanghai 200050, Peoples R China 2.City Univ Hong Kong, Dept Mech & Biomed Engn, Hong Kong 999077, Hong Kong, Peoples R China 3.City Univ Hong Kong, Dept Biol & Chem, Hong Kong 999077, Hong Kong, Peoples R China 4.Chinese Acad Sci, Inst High Energy Phys, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Multidisciplinary Res Div, Beijing 100049, Peoples R China 5.Zhejiang Univ, Coll Biomed Engn & Instrument Sci, Hangzhou 310027, Zhejiang, Peoples R China |
推荐引用方式 GB/T 7714 | Zhou, Xiaofeng,Li, Jianqian,Sun, Hongyan,et al. Controlled cell patterning on bioactive surfaces with special wettability[J]. Journal of bionic engineering,2017,14(3):440-447. |
APA | Zhou, Xiaofeng,Li, Jianqian,Sun, Hongyan,Hu, Yi,Che, Lufeng,&Wang, Zuankai.(2017).Controlled cell patterning on bioactive surfaces with special wettability.Journal of bionic engineering,14(3),440-447. |
MLA | Zhou, Xiaofeng,et al."Controlled cell patterning on bioactive surfaces with special wettability".Journal of bionic engineering 14.3(2017):440-447. |
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