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Controlled cell patterning on bioactive surfaces with special wettability
Zhou, Xiaofeng1; Li, Jianqian2; Sun, Hongyan3; Hu, Yi4; Che, Lufeng1,5; Wang, Zuankai2
刊名Journal of bionic engineering
2017-07-01
卷号14期号:3页码:440-447
关键词Cell patterning Wettability Superhydrophilic Surface chemistry Circulating tumor cells
ISSN号1672-6529
DOI10.1016/s1672-6529(16)60409-2
通讯作者Che, lufeng(lfche@zju.edu.cn) ; Wang, zuankai(zuanwang@cityu.edu.hk)
英文摘要The ability to control cell patterning on artificial substrates with various physicochemical properties is of essence for important implications in cytology and biomedical fields. despite extensive progress, the ability to control the cell-surface interaction is complicated by the complexity in the physiochemical features of bioactive surfaces. in particular, the manifestation of special wettability rendered by the combination of surface roughness and surface chemistry further enriches the cell-surface interaction. herein we investigated the cell adhesion behaviors of circulating tumor cells (ctcs) on topographically patterned but chemically homogeneous surfaces. harnessing the distinctive cell adhesion on surfaces with different topography, we further explored the feasibility of controlled cell patterning using periodic lattices of alternative topographies. we envision that our method provides a designer's toolbox to manage the extracellular environment.
WOS关键词CIRCULATING TUMOR-CELLS ; CANCER-CELLS ; EFFICIENT CAPTURE ; NANOWIRE ARRAYS ; BREAST-CANCER ; RELEASE ; NANOPARTICLES ; INTERFACES ; BACTERIA ; ADHESION
WOS研究方向Engineering ; Materials Science ; Robotics
WOS类目Engineering, Multidisciplinary ; Materials Science, Biomaterials ; Robotics
语种英语
出版者SCIENCE PRESS
WOS记录号WOS:000406572300002
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2176964
专题高能物理研究所
通讯作者Che, Lufeng; Wang, Zuankai
作者单位1.Chinese Acad Sci, Shanghai Inst Microsyst & Informat Technol, Sci & Technol Microsyst Lab, Shanghai 200050, Peoples R China
2.City Univ Hong Kong, Dept Mech & Biomed Engn, Hong Kong 999077, Hong Kong, Peoples R China
3.City Univ Hong Kong, Dept Biol & Chem, Hong Kong 999077, Hong Kong, Peoples R China
4.Chinese Acad Sci, Inst High Energy Phys, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Multidisciplinary Res Div, Beijing 100049, Peoples R China
5.Zhejiang Univ, Coll Biomed Engn & Instrument Sci, Hangzhou 310027, Zhejiang, Peoples R China
推荐引用方式
GB/T 7714
Zhou, Xiaofeng,Li, Jianqian,Sun, Hongyan,et al. Controlled cell patterning on bioactive surfaces with special wettability[J]. Journal of bionic engineering,2017,14(3):440-447.
APA Zhou, Xiaofeng,Li, Jianqian,Sun, Hongyan,Hu, Yi,Che, Lufeng,&Wang, Zuankai.(2017).Controlled cell patterning on bioactive surfaces with special wettability.Journal of bionic engineering,14(3),440-447.
MLA Zhou, Xiaofeng,et al."Controlled cell patterning on bioactive surfaces with special wettability".Journal of bionic engineering 14.3(2017):440-447.
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