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Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants
Yang, J.; Chen, K.; Zhang, G.; Yang, Q.-Y.; Li, Y.-S.; Huang, S.-Z.; Wang, Y.-L.; Yang, W.; Jiang, X.-J.; Yan, H.-X.
刊名European Journal of Medicinal Chemistry
2018
卷号Vol.143页码:1148-1164
关键词Drug resistance mutant Medullary thyroid cancer RET kinase Structure-activity relationship
ISSN号0223-5234
URL标识查看原文
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/1821703
专题四川大学
作者单位1.Department of Clinical Medicine, School of Medicine, Nankai University, Tianjin, China
2.a State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University/Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan, China
3.Key Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, West China School of Pharmacy, Sichuan University, Sichuan, China
推荐引用方式
GB/T 7714
Yang, J.,Chen, K.,Zhang, G.,et al. Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants[J]. European Journal of Medicinal Chemistry,2018,Vol.143:1148-1164.
APA Yang, J..,Chen, K..,Zhang, G..,Yang, Q.-Y..,Li, Y.-S..,...&Yang, S.-Y..(2018).Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.European Journal of Medicinal Chemistry,Vol.143,1148-1164.
MLA Yang, J.,et al."Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants".European Journal of Medicinal Chemistry Vol.143(2018):1148-1164.
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