Antibiotics and antibiotic resistance genes in global lakes: A review and meta-analysis

doi:10.1016/j.envint.2018.04.011

CORC > 武汉植物园 > 中国科学院武汉植物园

	Antibiotics and antibiotic resistance genes in global lakes: A review and meta-analysis
	Yang, Yuyi 1,2; Song, Wenjuan 3; Xing, Wei 1; Lin, Hui 4; Wang, Weibo 1; Du, Linna 5
刊名	ENVIRONMENT INTERNATIONAL
	2018-07-01
卷号	116 页码:60-73
关键词	Species sensitivity distributions Niche Aquatic biota Antibiotics Antibiotic resistance genes Meta-analysis
ISSN号	0160-4120
DOI	10.1016/j.envint.2018.04.011
英文摘要	Lakes are an important source of freshwater, containing nearly 90% of the liquid surface fresh water worldwide. Long retention times in lakes mean pollutants from discharges slowly circulate around the lakes and may lead to high ecological risk for ecosystem and human health. In recent decades, antibiotics and antibiotic resistance genes (ARGs) have been regarded as emerging pollutants. The occurrence and distribution of antibiotics and ARGs in global freshwater lakes are summarized to show the pollution level of antibiotics and ARGs and to identify some of the potential risks to ecosystem and human health. Fifty-seven antibiotics were reported at least once in the studied lakes. Our meta-analysis shows that sulfamethoxazole, sulfamerazine, sulfameter, tetracycline, oxytetracycline, erythromycin, and roxithromycin were found at high concentrations in both lake water and lake sediment. There is no significant difference in the concentration of sulfonamides in lake water from China and that from other countries worldwide; however, there was a significant difference in quinolones. Erythromycin had the lowest predicted hazardous concentration for 5% of the species (HC5) and the highest ecological risk in lakes. There was no significant difference in the concentration of sulfonamide resistance genes (sul1 and sul2) in lake water and river water. There is surprisingly limited research on the role of aquatic biota in propagation of ARGs in freshwater lakes. As an environment that is susceptible to cumulative build-up of pollutants, lakes provide an important environment to study the fate of antibiotics and transport of ARGs with a broad range of niches including bacterial community, aquatic plants and animals.
资助项目	National Natural Science Foundation of China[31400113] ; National Natural Science Foundation of China[31370479] ; Youth Innovation Promotion Association of Chinese Academy of Sciences[2015282] ; Wenzhou Science and Technology Major Project[2016N0031] ; Basic Public Welfare Research Projects in Zhejiang Province[LGF18E090007] ; State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control[2010DS700124-ZZ1802]
WOS研究方向	Environmental Sciences & Ecology
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000432745000009
内容类型	期刊论文
源URL	[http://202.127.146.157/handle/2RYDP1HH/5365]
专题	中国科学院武汉植物园
通讯作者	Yang, Yuyi; Xing, Wei
作者单位	1.Chinese Acad Sci, Wuhan Bot Garden, Key Lab Aquat Bot & Watershed Ecol, Wuhan 430074, Hubei, Peoples R China 2.Univ Dundee, Sch Life Sci, Dundee DD1 5EH, Scotland 3.Chinese Acad Sci, Xinjiang Inst Ecol & Geog, Urumqi 830011, Peoples R China 4.Zhejiang Acad Agr Sci, Inst Environm Resources & Soil Fertilizers, Hangzhou 310021, Zhejiang, Peoples R China 5.Wenzhou Vocat Coll Sci & Technol, Dept Agr & Biotechnol, Wenzhou 325006, Peoples R China
推荐引用方式 GB/T 7714	Yang, Yuyi,Song, Wenjuan,Xing, Wei,et al. Antibiotics and antibiotic resistance genes in global lakes: A review and meta-analysis[J]. ENVIRONMENT INTERNATIONAL,2018,116:60-73.
APA	Yang, Yuyi,Song, Wenjuan,Xing, Wei,Lin, Hui,Wang, Weibo,&Du, Linna.(2018).Antibiotics and antibiotic resistance genes in global lakes: A review and meta-analysis.ENVIRONMENT INTERNATIONAL,116,60-73.
MLA	Yang, Yuyi,et al."Antibiotics and antibiotic resistance genes in global lakes: A review and meta-analysis".ENVIRONMENT INTERNATIONAL 116(2018):60-73.