Dimeric sesquiterpene and thiophenes from the roots of Echinops latifolius

doi:10.1016/j.bmcl.2016.10.017

CORC > 武汉植物园 > 中国科学院武汉植物园

	Dimeric sesquiterpene and thiophenes from the roots of Echinops latifolius
	Jin, Qinghao 1,3; Lee, Jin Woo 1; Jang, Hari 1; Choi, Ji Eun 1; Kim, Hyung Sik 1; Lee, Dongho 2; Hong, Jin Tae 1; Lee, Mi Kyeong 1; Hwang, Bang Yeon 1
刊名	BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
	2016-12-15
卷号	26 期号:24 页码:5995-5998
关键词	Echinops latifolius Asteraceae Anti-inflammatory Dimeric sesquiterpene Thiophene
ISSN号	0960-894X
DOI	10.1016/j.bmcl.2016.10.017
英文摘要	Phytochemical investigation of the roots of Echinops latifolius led to the isolation of a new carbon skeleton dimeric sesquiterpene (1) and a new thiophene (2), along with six known compounds (3-8). Their structures and relative stereochemistry were elucidated by spectroscopic and spectrometric methods (H-1 and C-13 NMR, COSY, HSQC, HMBC, ROESY, and MS). All isolates were evaluated for their inhibition of LPS-induced NO production in RAW 264.7 cells. Compounds 4 and 5 exhibited the most potent inhibitory effects on NO production. (C) 2016 Elsevier Ltd. All rights reserved.
资助项目	Medical Research Center Program (MRC) through the National Research Foundation of Korea[2008-0062275]
WOS研究方向	Pharmacology & Pharmacy ; Chemistry
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000389784500032
内容类型	期刊论文
源URL	[http://202.127.146.157/handle/2RYDP1HH/3057]
专题	中国科学院武汉植物园
通讯作者	Hwang, Bang Yeon
作者单位	1.Chungbuk Natl Univ, Coll Pharm, Cheongju 28644, South Korea 2.Korea Univ, Coll Life Sci & Biotechnol, Seoul 02841, South Korea 3.Chinese Acad Sci, Wuhan Bot Garden, Key Lab Plant Germplasm Enhancement & Specialty A, Wuhan 430074, Peoples R China
推荐引用方式 GB/T 7714	Jin, Qinghao,Lee, Jin Woo,Jang, Hari,et al. Dimeric sesquiterpene and thiophenes from the roots of Echinops latifolius[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2016,26(24):5995-5998.
APA	Jin, Qinghao.,Lee, Jin Woo.,Jang, Hari.,Choi, Ji Eun.,Kim, Hyung Sik.,...&Hwang, Bang Yeon.(2016).Dimeric sesquiterpene and thiophenes from the roots of Echinops latifolius.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,26(24),5995-5998.
MLA	Jin, Qinghao,et al."Dimeric sesquiterpene and thiophenes from the roots of Echinops latifolius".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 26.24(2016):5995-5998.