Organ-specific accumulation, transportation, and elimination of methylmercury and inorganic mercury in a low Hg accumulating fish

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	Organ-specific accumulation, transportation, and elimination of methylmercury and inorganic mercury in a low Hg accumulating fish
	Liu, Fengjie; Peng, Xiaoyan; Wang, Wen-Xiong
刊名	Environmental Toxicology and Chemistry
	2016
卷号	35 期号:8 页码:2074-2083
关键词	Biokinetics Fish Hg Mehg Subcellular Distribution
英文摘要	Low mercury (Hg) concentrations down to several nanograms Hg per gram of wet tissue are documented in certain fish species such as herbivorous fish, and the underlying mechanisms remain speculative. In the present study, bioaccumulation and depuration patterns of inorganic Hg(II) and methylmercury (MeHg) in a herbivorous rabbitfish Siganus canaliculatus were investigated at organ and subcellular levels following waterborne or dietary exposures. The results showed that the efflux rate constants of Hg(II) and MeHg were 0.104d(-1) and 0.024d(-1), respectively, and are probably the highest rate constants recorded in fish thus far. The dietary MeHg assimilation efficiency (68%) was much lower than those in other fish species (approximate to 90%). The predominant distribution of MeHg in fish muscle was attributable to negligible elimination of MeHg from muscle (<0) and efficient elimination of MeHg from gills (0.12d(-1)), liver (0.17d(-1)), and intestine (0.20d(-1)), as well as efficient transportation of MeHg from other organs into muscle. In contrast, Hg(II) was much more slowly distributed into muscle but was efficiently eliminated by the intestine (0.13d(-1)). Subcellular distribution indicated that some specific membrane proteins in muscle were the primary binding pools for MeHg, and both metallothionein-like proteins and Hg-rich granules were the important components in eliminating both MeHg and Hg(II). Overall, the present study's results suggest that the low tissue Hg concentration in the rabbitfish was partly explained by its unique biokinetics.
学科主题	环境地球化学
语种	英语
公开日期	2017-11-20
内容类型	期刊论文
源URL	[http://ir.gyig.ac.cn:8080/handle/352002/6516]
专题	地球化学研究所_环境地球化学国家重点实验室_环境地球化学国家重点实验室_期刊论文
推荐引用方式 GB/T 7714	Liu, Fengjie,Peng, Xiaoyan,Wang, Wen-Xiong. Organ-specific accumulation, transportation, and elimination of methylmercury and inorganic mercury in a low Hg accumulating fish[J]. Environmental Toxicology and Chemistry,2016,35(8):2074-2083.
APA	Liu, Fengjie,Peng, Xiaoyan,&Wang, Wen-Xiong.(2016).Organ-specific accumulation, transportation, and elimination of methylmercury and inorganic mercury in a low Hg accumulating fish.Environmental Toxicology and Chemistry,35(8),2074-2083.
MLA	Liu, Fengjie,et al."Organ-specific accumulation, transportation, and elimination of methylmercury and inorganic mercury in a low Hg accumulating fish".Environmental Toxicology and Chemistry 35.8(2016):2074-2083.