Mn-containing titanium surface with favorable osteogenic and antimicrobial functions synthesized by PIII&D

doi:10.1016/j.colsurfb.2017.01.047

	Mn-containing titanium surface with favorable osteogenic and antimicrobial functions synthesized by PIII&D
	Yu, Le; Tian, Yaxin; Qiao, Yuqin; Liu, Xuanyong
刊名	Colloids and Surfaces B: Biointerfaces
	2017
卷号	152 页码:376-384
ISSN号	09277765
DOI	10.1016/j.colsurfb.2017.01.047
英文摘要	Reasonable incorporation of manganese into titanium is believed to be able to enhance the osteogenic and antibacterial activities of orthopedic implants. However, it is still a challenge to compromise Mn-induced cytotoxicity and better develop its biocompatibility and antimicrobial ability. To pinpoint this issue, a stable Mn ion release platform was created on Ti using plasma immersion ion implantation and deposition (PIII&D) technique. Compared with as-etched titanium, as a result, promoted antibacterial abilities against gram-negative bacteria species and enhanced osteogenic-related gene expressions on rBMMSC were observed on Mn-containing sample. Meanwhile, the Mn-containing samples showed no obvious cytotoxicity. Our results here provide insight to be better understanding the relationships between additives-induced biological performance and the dose, state, and stability of the doped element. © 2017
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/25593]
专题	中国科学院上海硅酸盐研究所
作者单位	State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai; 200050, China
推荐引用方式 GB/T 7714	Yu, Le,Tian, Yaxin,Qiao, Yuqin,et al. Mn-containing titanium surface with favorable osteogenic and antimicrobial functions synthesized by PIII&D[J]. Colloids and Surfaces B: Biointerfaces,2017,152:376-384.
APA	Yu, Le,Tian, Yaxin,Qiao, Yuqin,&Liu, Xuanyong.(2017).Mn-containing titanium surface with favorable osteogenic and antimicrobial functions synthesized by PIII&D.Colloids and Surfaces B: Biointerfaces,152,376-384.
MLA	Yu, Le,et al."Mn-containing titanium surface with favorable osteogenic and antimicrobial functions synthesized by PIII&D".Colloids and Surfaces B: Biointerfaces 152(2017):376-384.