Material chemistry of graphene oxide-based nanocomposites for theranostic nanomedicine

doi:10.1039/c7tb00680b

	Material chemistry of graphene oxide-based nanocomposites for theranostic nanomedicine
	Zhou, Yang 1; Jing, Xiangxiang 2; Chen, Yu 3
刊名	Journal of Materials Chemistry B
	2017
卷号	5 期号:32 页码:6451-6470
ISSN号	20507518
DOI	10.1039/c7tb00680b
英文摘要	The promising biomedical applications of graphene oxide (GO) have quickly catalyzed a generation of various GO-based functional composites with desirable nanostructures and composites to satisfy the specific biomedical applications of GO-based nanosystems. This comprehensive review summarizes and discusses the very recent developments in rational design, chemical fabrication and versatile biomedical applications of GO-based functional composites, including metal oxide-GO, metal-GO, fluorescent nanoparticles-GO, silica-GO, polymer-GO and other specific GO-based composite nanosystems. The integration of multi-components with GO is also discussed. Their versatile theranostic applications include diagnostic imaging-guided therapy (photothermal therapy, photodynamic therapy and chemotherapy), biosensing-based tumor detection, and synergistic therapy. The biocompatibility and biosafety of these promising GO-based nanocomposites are also briefly mentioned. Finally, the unresolved critical issues and challenges facing the design/fabrication/application of these unique GO-based functional nanocomposites are proposed to further promote their clinical translation. The unique multi-composition, nanostructure and unique theranostic performance of GO-based composites are highly expected to pave a new way for the development of highly efficient theranostic protocols/approaches for precise personalized biomedicine to benefit human health. © 2017 The Royal Society of Chemistry.
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/25626]
专题	中国科学院上海硅酸盐研究所
作者单位	1.Department of Ultrasound, Third People's Hospital of Chengdu City, Affiliated Hospital of Southwest, Jiaotong University, Chengdu; 610031, China; 2.Department of Ultrasound, Hainan General Hospital, Haikou; 570311, China; 3.State Key Lab of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai; 200050, China
推荐引用方式 GB/T 7714	Zhou, Yang,Jing, Xiangxiang,Chen, Yu. Material chemistry of graphene oxide-based nanocomposites for theranostic nanomedicine[J]. Journal of Materials Chemistry B,2017,5(32):6451-6470.
APA	Zhou, Yang,Jing, Xiangxiang,&Chen, Yu.(2017).Material chemistry of graphene oxide-based nanocomposites for theranostic nanomedicine.Journal of Materials Chemistry B,5(32),6451-6470.
MLA	Zhou, Yang,et al."Material chemistry of graphene oxide-based nanocomposites for theranostic nanomedicine".Journal of Materials Chemistry B 5.32(2017):6451-6470.