ZFLNC: a comprehensive and well-annotated database for zebrafish lncRNA | |
Hu, Xiang1; Chen, Wen1; Li, Jing; Huang, Shulan1; Xu, Xuling; Zhang, Xuan; Xiang, Shuanglin1; Liu, Changning | |
刊名 | DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION |
2018 | |
期号 | x页码:- |
关键词 | Long Noncoding Rnas Evolution Features Transcripts Mechanisms Expression Lincrnas Elements Network System |
ISSN号 | 1758-0463 |
DOI | 10.1093/database/bay114 |
英文摘要 | There is emerging evidence showing that lncRNAs can be involved in various critical biological processes. Zebrafish is a fully developed model system being used in a variety of basic research and biomedical studies. Hence, it is an ideal model organism to study the functions and mechanisms of lncRNAs. Here, we constructed ZFLNC-a comprehensive database of zebrafish lncRNA that is dedicated to providing a zebrafishbased platform for deep exploration of zebrafish lncRNAs and their mammalian counterparts to the relevant academic communities. The main data resources of lncRNAs in this database come from the NCBI, Ensembl, NONCODE, zflncRNApedia and literature. We also obtained lncRNAs as a supplement by analysing RNA-Seq datasets from SRA database. With these IncRNAs, we further carried out expression profiling, co-expression network prediction, Gene Ontology (GO)/Kyoto Encyclopedia of Genes and Genomes (KEGG)/Online Mendelian Inheritance in Man (OMIM) annotation and conservation analysis. As far as we know, ZFLNC is the most comprehensive and well-annotated database for zebrafish lncRNA. |
学科主题 | Mathematical & Computational Biology |
语种 | 英语 |
WOS记录号 | WOS:000450962500001 |
内容类型 | 期刊论文 |
源URL | [http://ir.xtbg.org.cn/handle/353005/11160] |
专题 | 西双版纳热带植物园_2012年后新成立研究组 |
通讯作者 | Liu, Changning |
作者单位 | 1.Chinese Acad Sci, CAS Key Lab Trop Plant Resources & Sustainable Us, Xishuangbanna Trop Bot Garden, Kunming 650223, Yunnan, Peoples R China 2.Hunan Normal Univ, Sch Life Sci, State Key Lab Dev Biol Freshwater Fish, Changsha 410081, Hunan, Peoples R China |
推荐引用方式 GB/T 7714 | Hu, Xiang,Chen, Wen,Li, Jing,et al. ZFLNC: a comprehensive and well-annotated database for zebrafish lncRNA[J]. DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION,2018(x):-. |
APA | Hu, Xiang.,Chen, Wen.,Li, Jing.,Huang, Shulan.,Xu, Xuling.,...&Liu, Changning.(2018).ZFLNC: a comprehensive and well-annotated database for zebrafish lncRNA.DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION(x),-. |
MLA | Hu, Xiang,et al."ZFLNC: a comprehensive and well-annotated database for zebrafish lncRNA".DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION .x(2018):-. |
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