Robust Self-assembly Properties of Glyceryl Decanoates Synthesized Under Wetting and Drying Cycles

doi:10.7503/cjcu20170857

	Robust Self-assembly Properties of Glyceryl Decanoates Synthesized Under Wetting and Drying Cycles
	Gao Jing 1; Huang Keke 1; Zhang Xianlong 2; Sun Yu 1; Feng Shouhua 1
刊名	CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
	2018-05-10
卷号	39 期号:5 页码:849-854
关键词	Condensation Wetting And Drying Cycle Glyceryl Decanoate Protocell Membrane Origin Of Life
ISSN号	0251-0790
DOI	10.7503/cjcu20170857
文献子类	Article
英文摘要	Nonenzymatic dehydration reactions of decanoic acid with glycerol has been reported to occur under mimicked prebiotic conditions at near neutral pH, yielding more evolved membrane precursor compound glyceryl decanoates. Two isomers of glyceryl monodecanoate were the main products after the condensation reactions, and the yield of glyceryl monodecanoates could be increased to 4. 7% with temperature rising to 90 degrees C. Vesicles were observed when the mixture after reactions was rehydrated. Experiments demonstrate that trace glyceryl decanoates produced in the mixture play a great role in robust self-assembly process, it is the existence of such lipid products that makes a lower critical vesicle concentration. Meanwhile, organic compounds have been encapsulated during the self-assembly of vesicles, so membranous structures provid a place for organic compounds to exist stably. The dehydration reactions at near neutral pH, followed by rehydration, are suitable for increasing protocell membrane stability to environment. It implies that the condensation reaction is plausible for yielding more complex amphiphiles and the appearance of membrane structures on the early earth.
WOS关键词	HYDROTHERMAL CONDITIONS ; AMINO-ACIDS ; POLYMERIZATION ; ACYLGLYCEROLS ; ENCAPSULATION ; AMPHIPHILES ; STABILITY ; MEMBRANES ; CHEMISTRY ; VESICLES
WOS研究方向	Chemistry
语种	英语
出版者	HIGHER EDUCATION PRESS
WOS记录号	WOS:000435335700002
资助机构	National Natural Science Foundation of China(21427802 ; 21671076 ; 21621001)
内容类型	期刊论文
源URL	[http://ir.qibebt.ac.cn/handle/337004/11369]
专题	中国科学院青岛生物能源与过程研究所
通讯作者	Feng Shouhua
作者单位	1.Jilin Univ, Coll Chem, State Key Lab Inorgan Synth & Preparat Chem, Changchun 130012, Jilin, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China
推荐引用方式 GB/T 7714	Gao Jing,Huang Keke,Zhang Xianlong,et al. Robust Self-assembly Properties of Glyceryl Decanoates Synthesized Under Wetting and Drying Cycles[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2018,39(5):849-854.
APA	Gao Jing,Huang Keke,Zhang Xianlong,Sun Yu,&Feng Shouhua.(2018).Robust Self-assembly Properties of Glyceryl Decanoates Synthesized Under Wetting and Drying Cycles.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,39(5),849-854.
MLA	Gao Jing,et al."Robust Self-assembly Properties of Glyceryl Decanoates Synthesized Under Wetting and Drying Cycles".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 39.5(2018):849-854.