Highly Sensitive and Selective Potassium Ion Detection Based on Graphene Hall Effect Biosensors

CORC > 宁波材料技术与工程研究所 > 中国科学院宁波材料技术与工程研究所 > 2018专题

	Highly Sensitive and Selective Potassium Ion Detection Based on Graphene Hall Effect Biosensors
	Liu, Xiangqi; Ye, Chen; Li, Xiaoqing; Cui, Naiyuan; Wu, Tianzhun; Du, Shiyu; Wei, Qiuping; Fu, Li; Yin, Jiancheng; Lin, Cheng-Te
刊名	MATERIALS
	2018
卷号	11 期号:3
关键词	G-quadruplex High-quality Dna Aptamers Solar-cells Films Nanoparticles Transistors Recognition Sensor
英文摘要	Potassium (K+) ion is an important biological substance in the human body and plays a critical role in the maintenance of transmembrane potential and hormone secretion. Several detection techniques, including fluorescent, electrochemical, and electrical methods, have been extensively investigated to selectively recognize K+ ions. In this work, a highly sensitive and selective biosensor based on single-layer graphene has been developed for K+ ion detection under Van der Pauw measurement configuration. With pre-immobilization of guanine-rich DNA on the graphene surface, the graphene devices exhibit a very low limit of detection (approximate to 1 nM) with a dynamic range of 1 nM-10 mu M and excellent K+ ion specificity against other alkali cations, such as Na+ ions. The origin of K+ ion selectivity can be attributed to the fact that the formation of guanine-quadruplexes from guanine-rich DNA has a strong affinity for capturing K+ ions. The graphene-based biosensors with improved sensing performance for K+ ion recognition can be applied to health monitoring and early disease diagnosis.
学科主题	Materials Science
语种	英语
公开日期	2018-12-04
内容类型	期刊论文
源URL	[http://ir.nimte.ac.cn/handle/174433/16768]
专题	2018专题
推荐引用方式 GB/T 7714	Liu, Xiangqi,Ye, Chen,Li, Xiaoqing,et al. Highly Sensitive and Selective Potassium Ion Detection Based on Graphene Hall Effect Biosensors[J]. MATERIALS,2018,11(3).
APA	Liu, Xiangqi.,Ye, Chen.,Li, Xiaoqing.,Cui, Naiyuan.,Wu, Tianzhun.,...&Lin, Cheng-Te.(2018).Highly Sensitive and Selective Potassium Ion Detection Based on Graphene Hall Effect Biosensors.MATERIALS,11(3).
MLA	Liu, Xiangqi,et al."Highly Sensitive and Selective Potassium Ion Detection Based on Graphene Hall Effect Biosensors".MATERIALS 11.3(2018).