Synthesis and Vacuum Cold Spray Deposition of Biofunctionalized Nanodiamond/Hydroxyapatite Nanocomposite for Biomedical Applications

CORC > 宁波材料技术与工程研究所 > 中国科学院宁波材料技术与工程研究所 > 2017专题

	Synthesis and Vacuum Cold Spray Deposition of Biofunctionalized Nanodiamond/Hydroxyapatite Nanocomposite for Biomedical Applications
	Gong, Yongfeng; Li, Deyan; Chen, Xiuyong; Zhang, Botao; Liu, Yi; Jin, Peipeng; Li, Hua
刊名	ADVANCED ENGINEERING MATERIALS
	2017
卷号	19 期号:12
关键词	Bone Morphogenetic Protein-2 Mesenchymal Stem-cells Drug-delivery Systems Nanodiamond Coatings Composite Titanium Biocompatibility Differentiation Microstructure
英文摘要	Insufficient biological performances of titanium alloys have been the long-standing problems for their clinical applications. Here, we report synthesis of novel hydroxyapatite/nanodiamond-bone morphogenetic protein 2 (HA-ND/BMP2) composite powder and their coatings deposited by vacuum cold spray operated at room temperature. The microstructure and chemistry of the HA-ND/BMP2 powder and coatings are characterized by transmission electron microscopy, field-emission scanning electron microscopy, thin-film X-ray diffraction, Raman spectrometry, and X-ray photoelectron spectroscopy. In vitro growth assay of osteoblasts on the coatings showed that the biofunctionalized nanodiamonds promoted cell adhesion and proliferation. This study provides a promising technical route for constructing biofunctionalized nanocomposites coatings for potential biomedical applications.
学科主题	Polymer Science
语种	英语
公开日期	2018-12-04
内容类型	期刊论文
源URL	[http://ir.nimte.ac.cn/handle/174433/17495]
专题	2017专题
推荐引用方式 GB/T 7714	Gong, Yongfeng,Li, Deyan,Chen, Xiuyong,et al. Synthesis and Vacuum Cold Spray Deposition of Biofunctionalized Nanodiamond/Hydroxyapatite Nanocomposite for Biomedical Applications[J]. ADVANCED ENGINEERING MATERIALS,2017,19(12).
APA	Gong, Yongfeng.,Li, Deyan.,Chen, Xiuyong.,Zhang, Botao.,Liu, Yi.,...&Li, Hua.(2017).Synthesis and Vacuum Cold Spray Deposition of Biofunctionalized Nanodiamond/Hydroxyapatite Nanocomposite for Biomedical Applications.ADVANCED ENGINEERING MATERIALS,19(12).
MLA	Gong, Yongfeng,et al."Synthesis and Vacuum Cold Spray Deposition of Biofunctionalized Nanodiamond/Hydroxyapatite Nanocomposite for Biomedical Applications".ADVANCED ENGINEERING MATERIALS 19.12(2017).