Synthesis and Properties of Shape Memory Poly(gamma-Benzyl-L-Glutamate)-b-Poly(Propylene Glycol)-b-Poly(gamma-Benzyl-L-Glutamate)

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	Synthesis and Properties of Shape Memory Poly(gamma-Benzyl-L-Glutamate)-b-Poly(Propylene Glycol)-b-Poly(gamma-Benzyl-L-Glutamate)
	Jiang, Yuanzhang; Hu, Jinlian; Gu, Lin
刊名	APPLIED SCIENCES-BASEL
	2017
卷号	7 期号:12
关键词	Poly-l-cysteine Biomedical Applications Secondary Structure Body-temperature Block-copolymers Polypeptides Behavior Polyurethane
英文摘要	Shape memory polymers (SMPs) have attracted much attention as an important class of stimuli-responsive materials for biomedical applications. For SMP-based biomaterials, in addition to suitable shape recovery performances, their mechanical properties, biodegradability, biocompatibility, and sterilizability needs to be considered. Polypeptides can satisfy the requirements outlined above. However, there are few reports on shape memory polypeptides. In this paper, shape memory poly(gamma-benzyl-L-glutamate) (PBLG-PPG-PBLG) was synthesized by ring-opening polymerization of gamma-benzyl-L-glutamate-N-carboxyanhydrides (BLG-NCA) with poly(propylene glycol) bis(2-aminopropyl ether) as the macroinitiator. H-1 Nuclear Magnetic Resonance (NMR) and Fourier-Transform Infrared Spectroscopy (FTIR) were used to characterize the structure of the obtained PBLG-PPG-PBLG. The FTIR analysis showed that PBLG-PPG-PBLG has alpha-helical and beta-sheet structures. PBLG-PPG-PBLG has good shape memory properties, its shape recovery time is less than 120 s, and its shape recovery rate is 100%. In this study, we reported a simple synthetic method to obtain intelligent polypeptide materials, which will be used in many biomedical applications.
学科主题	Science & Technology - Other Topics
语种	英语
公开日期	2018-12-04
内容类型	期刊论文
源URL	[http://ir.nimte.ac.cn/handle/174433/17494]
专题	2017专题
推荐引用方式 GB/T 7714	Jiang, Yuanzhang,Hu, Jinlian,Gu, Lin. Synthesis and Properties of Shape Memory Poly(gamma-Benzyl-L-Glutamate)-b-Poly(Propylene Glycol)-b-Poly(gamma-Benzyl-L-Glutamate)[J]. APPLIED SCIENCES-BASEL,2017,7(12).
APA	Jiang, Yuanzhang,Hu, Jinlian,&Gu, Lin.(2017).Synthesis and Properties of Shape Memory Poly(gamma-Benzyl-L-Glutamate)-b-Poly(Propylene Glycol)-b-Poly(gamma-Benzyl-L-Glutamate).APPLIED SCIENCES-BASEL,7(12).
MLA	Jiang, Yuanzhang,et al."Synthesis and Properties of Shape Memory Poly(gamma-Benzyl-L-Glutamate)-b-Poly(Propylene Glycol)-b-Poly(gamma-Benzyl-L-Glutamate)".APPLIED SCIENCES-BASEL 7.12(2017).