Activity Patterns Elicited by Airflow in the Olfactory Bulb and Their Possible Functions

doi:10.1523/JNEUROSCI.2210-17.2017

CORC > 武汉物理与数学研究所 > 中国科学院武汉物理与数学研究所 > 磁共振应用研究部

	Activity Patterns Elicited by Airflow in the Olfactory Bulb and Their Possible Functions
	Wang, Li 2; Li, Bo 2; Wu, Ruiqi 2; Liu, Yue 1; Xu, Fuqiang 1,2
刊名	JOURNAL OF NEUROSCIENCE
	2017-11-01
卷号	37 期号:44 页码:10700-10711
关键词	Airflow Map Airflow Rhythm Functional Mri Mechanosensitivity Olfactory Bulb
DOI	10.1523/JNEUROSCI.2210-17.2017
文献子类	Article
英文摘要	Olfactory sensory neurons (OSNs) can sense both odorants and airflows. In the olfactory bulb (OB), the coding of odor information has been well studied, but the coding of mechanical stimulation is rarely investigated. Unlike odor-sensing functions of OSNs, the airflow-sensing functions of OSNs are also largely unknown. Here, the activity patterns elicited by mechanical airflow in male rat OBs were mapped using fMRI and correlated with local field potential recordings. In an attempt to reveal possible functions of airflow sensing, the relationship between airflow patterns and physiological parameters was also examined. We found the following: (1) the activity pattern in the OB evoked by airflow in the nasal cavity was more broadly distributed than patterns evoked by odors; (2) the pattern intensity increases with total airflow, while the pattern topography with total airflow remains almost unchanged; and (3) the heart rate, spontaneous respiratory rate, and electroencephalograph power in the beta band decreased with regular mechanical airflow in the nasal cavity. The mapping results provide evidence that the signals elicited by mechanical airflow in OSNs are transmitted to the OB, and that the OB has the potential to code and process mechanical information. Our functional data indicate that airflow rhythm in the olfactory system can regulate the physiological and brain states, providing an explanation for the effects of breath control in meditation, yoga, and Taoism practices.
WOS关键词	RECEPTOR NEURON INPUT ; ODOR MAPS ; SENSORY NEURONS ; GLOMERULAR LAYER ; NETWORK ACTIVITY ; FMRI RESPONSES ; RAT ; OSCILLATIONS ; RESPIRATION ; ORGANIZATION
WOS研究方向	Neurosciences & Neurology
语种	英语
WOS记录号	WOS:000414190300015
资助机构	National Basic Research Program (973 Program) of China(2015CB755601) ; National Basic Research Program (973 Program) of China(2015CB755601) ; National Natural Science Foundation of China(81661148053 ; National Natural Science Foundation of China(81661148053 ; Strategic Priority Research Program of Chinese Academy of Sciences(XDB02050005) ; Strategic Priority Research Program of Chinese Academy of Sciences(XDB02050005) ; 91632303) ; 91632303) ; National Basic Research Program (973 Program) of China(2015CB755601) ; National Basic Research Program (973 Program) of China(2015CB755601) ; National Natural Science Foundation of China(81661148053 ; National Natural Science Foundation of China(81661148053 ; Strategic Priority Research Program of Chinese Academy of Sciences(XDB02050005) ; Strategic Priority Research Program of Chinese Academy of Sciences(XDB02050005) ; 91632303) ; 91632303)
内容类型	期刊论文
源URL	[http://ir.wipm.ac.cn/handle/112942/11544]
专题	武汉物理与数学研究所_磁共振应用研究部
作者单位	1.Wuhan Natl Lab Optoelect, Wuhan 430074, Hubei, Peoples R China 2.Chinese Acad Sci, State Key Lab Magnet Resonance & Atom & Mol Phys, Ctr Excellence Brain Sci & Intelligent Technol, Wuhan Inst Phys & Math,Key Lab Magnet Resonance B, Wuhan 430071, Hubei, Peoples R China
推荐引用方式 GB/T 7714	Wang, Li,Li, Bo,Wu, Ruiqi,et al. Activity Patterns Elicited by Airflow in the Olfactory Bulb and Their Possible Functions[J]. JOURNAL OF NEUROSCIENCE,2017,37(44):10700-10711.
APA	Wang, Li,Li, Bo,Wu, Ruiqi,Liu, Yue,&Xu, Fuqiang.(2017).Activity Patterns Elicited by Airflow in the Olfactory Bulb and Their Possible Functions.JOURNAL OF NEUROSCIENCE,37(44),10700-10711.
MLA	Wang, Li,et al."Activity Patterns Elicited by Airflow in the Olfactory Bulb and Their Possible Functions".JOURNAL OF NEUROSCIENCE 37.44(2017):10700-10711.