Developmental selenium exposure and health risk in daily foodstuffs: A systematic review and meta-analysis
Ullah, Habib1,2; Munir, Mehr Ahmed Mujtaba2; Mian, Md Manik2; Abbas, Qumber2; Ali, Muhammad Ubaid2; Yousaf, Balal2; Liu, Guijian1,2
刊名ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
2018-03-01
卷号149期号:2018页码:291-306
关键词Selenium Dietary Intake Selenoprotein Bioavailability Antioxidant
DOI10.1016/j.ecoenv.2017.11.056
文献子类Review
英文摘要Selenium (Se) is a trace mineral and an essential nutrient of vital importance to human health in trace amounts. It acts as an antioxidant in both humans and animals, immunomodulator and also involved in the control of specific endocrine pathways. The aim of this work is to provide a brief knowledge on selenium content in daily used various foodstuffs, nutritional requirement and its various health consequences. In general, fruits and vegetables contain low content of selenium, with some exceptions. Selenium level in meat, eggs, poultry and seafood is usually high. For most countries, cereals, legumes, and derivatives are the major donors to the dietary selenium intake. Low level of selenium has been related with higher mortality risk, dysfunction of an immune system, and mental failure. Selenium supplementation or higher selenium content has antiviral outcomes and is necessary for effective reproduction of male and female, also decreases the threat of chronic disease (auto immune thyroid). Generally, some advantages of higher content of selenium have been shown in various potential studies regarding lung, colorectal, prostate and bladder cancers risk, nevertheless results depicted from different trials have been diverse, which perhaps indicates the evidence that supplementation will merely grant advantage if the intakes of a nutrient is deficient. In conclusion, the over-all people should be advised against the usage of Se supplements for prevention of cardiovascular, hepatopathies, or cancer diseases, as advantages of Se supplements are still ambiguous, and their haphazard usage could result in an increased Se toxicity risk. The associations among Se intake/status and health, or disease risk, are complicated and need exposition to notify medical practice, to improve dietary recommendations, and to develop adequate communal health guidelines.
WOS关键词PROSTATE-CANCER RISK ; POTENTIALLY TOXIC ELEMENTS ; DAILY DIETARY-INTAKE ; GLUTATHIONE-PEROXIDASE ACTIVITY ; SERUM SELENIUM ; TRACE-ELEMENTS ; FOOD-CHAIN ; FOLLOW-UP ; IN-VITRO ; ANTIOXIDANT SUPPLEMENTATION
WOS研究方向Environmental Sciences & Ecology ; Toxicology
语种英语
WOS记录号WOS:000424068900038
内容类型期刊论文
源URL[http://ir.ieecas.cn/handle/361006/5194]  
专题地球环境研究所_黄土与第四纪地质国家重点实验室(2010~)
作者单位1.Chinese Acad Sci, Inst Earth Environm, State Key Lab Loess & Quaternary Geol, Xian 710075, Shaanxi, Peoples R China
2.Univ Sci & Technol China, Sch Earth & Space Sci, CAS Key Lab Crust Mantle Mat & Environm, Hefei 230026, Anhui, Peoples R China
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Ullah, Habib,Munir, Mehr Ahmed Mujtaba,Mian, Md Manik,et al. Developmental selenium exposure and health risk in daily foodstuffs: A systematic review and meta-analysis[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2018,149(2018):291-306.
APA Ullah, Habib.,Munir, Mehr Ahmed Mujtaba.,Mian, Md Manik.,Abbas, Qumber.,Ali, Muhammad Ubaid.,...&Liu, Guijian.(2018).Developmental selenium exposure and health risk in daily foodstuffs: A systematic review and meta-analysis.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,149(2018),291-306.
MLA Ullah, Habib,et al."Developmental selenium exposure and health risk in daily foodstuffs: A systematic review and meta-analysis".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 149.2018(2018):291-306.
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