Organic nanostructure-based probes for two-photon imaging of mitochondria and microbes with emission between 430 nm and 640 nm

doi:10.1039/c7nr00342k

	Organic nanostructure-based probes for two-photon imaging of mitochondria and microbes with emission between 430 nm and 640 nm
	Yang, XL; Wang, NX; Zhang, LM; Dai, LR; Shao, HW; Jiang, XY; Shao, HW (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Sichuan, Peoples R China.; Jiang, XY (reprint author), Natl Ctr NanoSci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China.
刊名	NANOSCALE
	2017
卷号	9 期号:14 页码:4770（1-7）
DOI	10.1039/c7nr00342k
产权排序	1
文献子类	Article
英文摘要	Multi-photon excitation and versatile fluorescent probes are in high need for biological imaging, since one probe can satisfy many needs as a biosensor. Herein we synthesize a series of two-photon excited probes based on tetraphenylethene (TPE) structures (TPE-Acr, TPE-Py, and TPE-Quino), which can image both mammalian cells and bacteria based on aggregation-induced emission (AIE) without washing them. Because of cationic moieties, the fluorescent molecules can aggregate into nanoscale fluorescent organic nanoscale dots to image mitochondria and bacteria with tunable emissions using both one-photon and two-photon excitation. Our research demonstrates that these AIE-dots expand the functions of luminescent organic dots to construct efficient fluorescent sensors applicable to both one-photon and two-photon excitation for bio-imaging of bacteria and mammalian cells.
学科主题	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种	英语
资助机构	We thank the Ministry of Science and Technology of China (2013YQ190467), Chinese Academy of Sciences (XDA09030305) and the National Science Foundation of China (81361140345, 51373043, 21535001) for financial support. ; Ministry of Science and Technology of China [2013YQ190467] ; We thank the Ministry of Science and Technology of China (2013YQ190467), Chinese Academy of Sciences (XDA09030305) and the National Science Foundation of China (81361140345, 51373043, 21535001) for financial support. ; Ministry of Science and Technology of China [2013YQ190467] ; Chinese Academy of Sciences [XDA09030305] ; Chinese Academy of Sciences [XDA09030305] ; National Science Foundation of China [81361140345, 51373043, 21535001] ; National Science Foundation of China [81361140345, 51373043, 21535001] ; We thank the Ministry of Science and Technology of China (2013YQ190467), Chinese Academy of Sciences (XDA09030305) and the National Science Foundation of China (81361140345, 51373043, 21535001) for financial support. ; Ministry of Science and Technology of China [2013YQ190467] ; We thank the Ministry of Science and Technology of China (2013YQ190467), Chinese Academy of Sciences (XDA09030305) and the National Science Foundation of China (81361140345, 51373043, 21535001) for financial support. ; Ministry of Science and Technology of China [2013YQ190467] ; Chinese Academy of Sciences [XDA09030305] ; Chinese Academy of Sciences [XDA09030305] ; National Science Foundation of China [81361140345, 51373043, 21535001] ; National Science Foundation of China [81361140345, 51373043, 21535001]
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/29244]
专题	成都生物研究所_天然产物研究
通讯作者	Shao, HW (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Sichuan, Peoples R China.; Jiang, XY (reprint author), Natl Ctr NanoSci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China.
推荐引用方式 GB/T 7714	Yang, XL,Wang, NX,Zhang, LM,et al. Organic nanostructure-based probes for two-photon imaging of mitochondria and microbes with emission between 430 nm and 640 nm[J]. NANOSCALE,2017,9(14):4770（1-7）.
APA	Yang, XL.,Wang, NX.,Zhang, LM.,Dai, LR.,Shao, HW.,...&Jiang, XY .(2017).Organic nanostructure-based probes for two-photon imaging of mitochondria and microbes with emission between 430 nm and 640 nm.NANOSCALE,9(14),4770（1-7）.
MLA	Yang, XL,et al."Organic nanostructure-based probes for two-photon imaging of mitochondria and microbes with emission between 430 nm and 640 nm".NANOSCALE 9.14(2017):4770（1-7）.